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超声直方图评估局部晚期宫颈癌患者同步放化疗的早期反应:一项可行性研究

Ultrasonic histogram assessment of early response to concurrent chemo-radiotherapy in patients with locally advanced cervical cancer: a feasibility study.

作者信息

Xu Yan, Ru Tong, Zhu Lijing, Liu Baorui, Wang Huanhuan, Zhu Li, He Jian, Liu Song, Zhou Zhengyang, Yang Xiaofeng

机构信息

Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China; Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.

Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.

出版信息

Clin Imaging. 2018 May-Jun;49:144-149. doi: 10.1016/j.clinimag.2018.01.002. Epub 2018 Jan 9.

DOI:10.1016/j.clinimag.2018.01.002
PMID:29414509
Abstract

PURPOSE

To monitor early response for locally advanced cervical cancers undergoing concurrent chemo-radiotherapy (CCRT) by ultrasonic histogram.

METHODS

B-mode ultrasound examinations were performed at 4 time points in thirty-four patients during CCRT. Six ultrasonic histogram parameters were used to assess the echogenicity, homogeneity and heterogeneity of tumors.

RESULTS

I increased rapidly since the first week after therapy initiation, whereas W, W and A changed significantly at the second week. The average ultrasonic histogram progressively moved toward the right and converted into more symmetrical shape.

CONCLUSION

Ultrasonic histogram could be served as a potential marker to monitor early response during CCRT.

摘要

目的

通过超声直方图监测局部晚期宫颈癌同步放化疗(CCRT)的早期反应。

方法

对34例接受CCRT的患者在4个时间点进行B超检查。使用6个超声直方图参数评估肿瘤的回声性、均匀性和异质性。

结果

自治疗开始后第一周起I迅速升高,而W、W和A在第二周有显著变化。平均超声直方图逐渐向右移动并转变为更对称的形状。

结论

超声直方图可作为监测CCRT早期反应的潜在标志物。

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