掌跖角化-牙周破坏综合征。三例患者口服维甲酸治疗成功。

Papillon-Lefèvre syndrome. Successful treatment with oral retinoids in three patients.

作者信息

el Darouti M A, Al Raubaie S M, Eiada M A

机构信息

Department of Dermatology, Cairo University Faculty of Medicine, Egypt.

出版信息

Int J Dermatol. 1988 Jan-Feb;27(1):63-6. doi: 10.1111/j.1365-4362.1988.tb02344.x.

DOI:10.1111/j.1365-4362.1988.tb02344.x

PMID:2964426

Abstract

Papillon-Lefèvre syndrome is a rare autosomal recessive disorder of palmoplantar keratinization in which there is a unique association of the palmoplantar hyperkeratosis and premature loss of both deciduous and permanent teeth. We report three patients with papillon-lefèvre syndrome who showed a remarkable degree of improvement after treatment with an oral retinoid.

摘要

掌跖角化病综合征是一种罕见的常染色体隐性遗传性掌跖角化障碍性疾病，其特征为掌跖过度角化与乳牙和恒牙过早缺失的独特关联。我们报告了3例掌跖角化病综合征患者，他们在接受口服维甲酸治疗后有显著改善。