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宫本疏螺旋体——神经莱姆病的新病原体?

Borrelia miyamotoi - new etiologic agent of neuroborreliosis?

作者信息

Fiecek Beata, Chmielewski Tomasz, Tylewska-Wierzbanowska Stanisława

机构信息

National Institute of Public Health - National Institute of Hygiene, Warsaw Laboratory of Rickettsiae, Chlamydiae and Spirochetes

出版信息

Przegl Epidemiol. 2017;71(4):531-538.

PMID:29415531
Abstract

Borrelia miyamotoi spirochetes discovered in Ixodes persulcatus ticks in Japan, in 1994 and documented in ticks and rodents in moderate climate zone of northern hemisphere. They belong to tick-borne relapsing fever group spirochetes. Borrelia miyamotoi is an etiologic agent of B.miyamotoi disease with acute febrile illness, including fever, headache, dizziness, fatigue, chills, and muscle and joint pain. Recurrence of fever has been observer in more than 10% patients. In some patients meningoencephalitis, encephalitis and cranial neuritis were observed. Laboratory recognition is based mainly upon PCR testing. Serological testing is limited due to inaccessibility of tests.

摘要

1994年在日本全沟硬蜱中发现了宫本疏螺旋体,随后在北半球温带气候区的蜱类和啮齿动物中也有记录。它们属于蜱传回归热群螺旋体。宫本疏螺旋体是宫本疏螺旋体病的病原体,可引起急性发热性疾病,包括发热、头痛、头晕、疲劳、寒战以及肌肉和关节疼痛。超过10%的患者出现发热复发。部分患者还出现了脑膜脑炎、脑炎和颅神经炎。实验室诊断主要基于聚合酶链反应(PCR)检测。由于检测方法难以获得,血清学检测受到限制。

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A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods.
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