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[激光多普勒振动测量法在耳科学中的新临床应用]

[New clinical applications for laser Doppler vibrometry in otology].

作者信息

Strenger T, Brandstetter M, Stark T, Böhnke F

机构信息

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Klinikum Augsburg (Süd), Sauerbruchstr. 6, 86179, Augsburg, Deutschland.

HNO-Praxis Holzkirchen, Holzkirchen, Deutschland.

出版信息

HNO. 2018 Apr;66(4):265-279. doi: 10.1007/s00106-018-0473-x.

DOI:10.1007/s00106-018-0473-x
PMID:29417191
Abstract

BACKGROUND

An instrument to measure vibration in the middle ear needs to be sensitive enough to detect displacement on a nanometer scale, yet not affect the vibration itself. Numerous techniques have been described in the literature, but laser Doppler vibrometry (LDV) has nowadays become established as the standard method in hearing research.

OBJECTIVE

This article aims to present possible clinical applications of an LDV system in otology.

MATERIALS AND METHODS

A commercially available single-point vibrometer was used. Measurements were carried out both with the sensor head mounted on an operating microscope and as a handheld device with the sensor head manually inserted in the ear canal. For the latter, a custom-made unit containing an electrically tunable lens was attached to the sensor head. Middle ear vibrations were measured in a temporal bone model as well as in patients during and after implantation of a Vibrant Soundbridge (VSB; MED-EL Corp., Durham/NC, USA).

RESULTS

Different types of middle ear pathologies can be distinguished by the frequency response of the umbo. The LDV technique can be used for intraoperative quantification of the coupling quality of the VSB's Floating Mass Transducer (FMT; MED-EL) to the ossicle chain during VSB implantation. Postoperatively, the method serves as a follow-up testing tool if a deterioration in aided hearing threshold occurs. The measurement can reveal changes in the umbo transfer function, e. g., due to middle ear scarring or dislocation of the FMT.

CONCLUSION

Many clinical questions in otology can be addressed by LDV. However, due to the high acquisition costs of an LDV system, the relatively large instrumental setup, and the large inter-ear variability of middle-ear function, the technique has not (yet) become established in clinical routine.

摘要

背景

用于测量中耳振动的仪器需要足够灵敏,以检测纳米级别的位移,同时又不影响振动本身。文献中已描述了众多技术,但激光多普勒振动测量法(LDV)如今已成为听力研究中的标准方法。

目的

本文旨在介绍LDV系统在耳科学中的可能临床应用。

材料与方法

使用了一款市售的单点振动计。测量时,传感器头既可以安装在手术显微镜上,也可以作为手持设备,将传感器头手动插入耳道。对于后者,在传感器头上连接了一个包含电可调透镜的定制装置。在颞骨模型以及植入了Vibrant Soundbridge(VSB;MED-EL公司,美国北卡罗来纳州达勒姆)的患者手术期间及术后,测量中耳振动。

结果

通过鼓膜脐的频率响应可区分不同类型的中耳病变。LDV技术可用于术中量化VSB植入期间其浮动质量传感器(FMT;MED-EL)与听骨链的耦合质量。术后,如果助听阈值恶化,该方法可作为随访测试工具。测量可揭示鼓膜脐传递函数的变化,例如由于中耳瘢痕形成或FMT脱位导致的变化。

结论

耳科学中的许多临床问题都可以通过LDV来解决。然而,由于LDV系统的购置成本高、仪器设置相对庞大,以及中耳功能在两耳间的变异性较大,该技术尚未成为临床常规应用方法。

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本文引用的文献

1
Prospective evaluation of reliability of cone-beam computed tomography in detecting different position of vibroplasty middle ear implants.前瞻性评估锥形束 CT 检测不同位置中耳振动成型植入物的可靠性。
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Presentation of floating mass transducer and Vibroplasty couplers on CT and cone beam CT.在 CT 和锥形束 CT 上呈现浮动质量换能器和 Vibroplasty 耦合器。
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Application of active middle ear implants in patients with severe mixed hearing loss.
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Otol Neurotol. 2012 Apr;33(3):297-301. doi: 10.1097/MAO.0b013e3182487f98.
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The benefit of the reverse transfer function in the fitting process of the Vibrant Soundbridge middle ear implant.
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MRI scanning in patients implanted with a Vibrant Soundbridge.MRI 扫描在植入 Vibrant Soundbridge 的患者中的应用。
Laryngoscope. 2011 Jul;121(7):1532-5. doi: 10.1002/lary.21779. Epub 2011 Jun 6.
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New aspects in the clinical diagnosis of otosclerosis using laser Doppler vibrometry.应用激光多谱勒测振仪对耳硬化症的临床诊断的新观点。
Otol Neurotol. 2009 Dec;30(8):1049-57. doi: 10.1097/MAO.0b013e31819e622b.
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Differential intracochlear sound pressure measurements in normal human temporal bones.正常人类颞骨内耳蜗内声压的差异测量
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Clinical utility of laser-Doppler vibrometer measurements in live normal and pathologic human ears.激光多普勒振动计测量在正常和病理状态下活人耳中的临床应用。
Ear Hear. 2008 Jan;29(1):3-19. doi: 10.1097/AUD.0b013e31815d63a5.
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A normative study of tympanic membrane motion in humans using a laser Doppler vibrometer (LDV).一项使用激光多普勒振动计(LDV)对人类鼓膜运动进行的规范性研究。
Hear Res. 2004 Jan;187(1-2):85-104. doi: 10.1016/s0378-5955(03)00332-0.