Rohde Judith, Majzoub-Altweck Monir, Falkenau Almuth, Hermanns Walter, Burrough Eric R, Ritzmann Mathias, Stadler Julia
Institute for Microbiology, University of Veterinary Medicine, Foundation, Hannover, Germany.
Institute of Veterinary Pathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.
Vet Rec. 2018 Feb 17;182(7):195. doi: 10.1136/vr.104705. Epub 2018 Feb 1.
The anaerobic intestinal spirochaete ) was first described in 2007 but since then no further isolates have been reported from pigs. Accordingly, when the species was validly published in 2016, the overall occurrence and clinical relevance in pigs were unknown. In a fattening farm in southern Germany, mucohaemorrhagic diarrhoea was observed in 60 per cent (750 animals) of the finisher pigs. A diagnostic workup including culture, culture, specific, -specific and -specific multiplex PCR and postmortem examination of severely affected pigs was performed. Tests for species, and were all negative. Gross and microscopic lesions were in agreement with dysentery and spirochaetes could be demonstrated by silver staining in tissue samples of the caecum at the ileal papilla. was cultured from faeces or colon of all (five) animals sampled and identified using -RFLP, partial -gene-sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). According to the initial report from Scandinavia, can be isolated from birds and cross-species infection could be demonstrated infecting pigs with an avian isolate. Thus outdoor production as in the case presented here and international trade may pose a risk for infection of naive herds.
厌氧肠道螺旋体于2007年首次被描述，但自那时起，尚未有从猪身上分离出更多菌株的报道。因此，当该物种于2016年被正式发表时，其在猪群中的总体发生率和临床相关性尚不清楚。在德国南部的一个育肥场，60%（750头）的育肥猪出现了黏液出血性腹泻。对严重受影响的猪进行了包括培养、特定的多重聚合酶链反应（PCR）以及死后检查在内的诊断性检查。对该物种的检测均为阴性。大体和微观病变与痢疾相符，在回肠乳头处盲肠的组织样本中，通过银染色可显示螺旋体。从所有（5头）采样动物的粪便或结肠中培养出了该菌，并使用限制性片段长度多态性分析（RFLP）、部分基因测序和基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）进行了鉴定。根据斯堪的纳维亚的初步报告，该菌可从鸟类中分离出来，并且可以证明禽类分离株可感染猪，从而导致跨物种感染。因此，如本文所述的户外养殖方式以及国际贸易可能会对未感染猪群构成感染风险。
