Parra-Jaramillo Katherine, Chiriboga-Ponce Rosa F
Facultad de Medicina-Carrera de Bioquímica Clínica. Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Centro de Investigación para la salud en América Latina. Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Gac Med Mex. 2018;154(1):22-25. doi: 10.24875/GMM.17002739.
The presence of weak variants of blood type A represents a challenge in the practice of immunohematology for discrepancies in the time of the classification. It is common in blood banks to perform a forward and reverse typing for the purpose of confirming the blood type, but not all the people with a subgroup A2 have developed anti-A1 antibodies.
We present a descriptive, observational and transversal study that establishes the proportion of subgroups of A antigen with the analysis of manual tube technique and monoclonal antibodies like anti-A, anti-A1 (Dolichus biflorus lectins extract) and anti-H.
The analysis involved a total of 818 samples of voluntary blood donor, selected by random sampling, which were initially classified as 737 of Type A, and 81 as Type AB, with a confidence level of 95% (alpha error of 5% and 3% of precision).
The present study evaluated the existence of the subgroups A1, A2, A1B, A2B, A intermediate and A intB.
It is recommended the identification of subgroups in different types of blood in the laboratory and blood banks.
