Stonesifer K J, Benson N A, Ryden S E, Pawliger D F, Braylan R C
Blood. 1986 Aug;68(2):426-9.
The flow cytometric analysis of DNA content in cells obtained from a case of Lennert's lymphoma demonstrated the presence of a discrete hypotetraploid cell population. Correlated multiparameter analysis of DNA, light scatter, and surface antigens by flow cytometry showed that the hypotetraploid cells were intermediate to large cells expressing T11, T3, and T4 antigens and lacking B1 and T8 antigens. These findings suggest that Lennert's lymphoma represents a malignant neoplasm of T-helper lymphocytes.
对一例 Lennert 淋巴瘤患者的细胞进行 DNA 含量的流式细胞术分析,结果显示存在离散的亚四倍体细胞群。通过流式细胞术对 DNA、光散射和表面抗原进行相关多参数分析表明,亚四倍体细胞为表达 T11、T3 和 T4 抗原且缺乏 B1 和 T8 抗原的中等大小至大细胞。这些发现提示 Lennert 淋巴瘤代表 T 辅助淋巴细胞的恶性肿瘤。