2012 - 2013年塞拉利昂博城乙肝表面抗原（HBsAg）血清流行率
Seroprevalence of hepatitis B surface antigen (HBsAg) in Bo, Sierra Leone, 2012-2013.
作者信息
Ansumana Rashid, Dariano Donald F, Jacobsen Kathryn H, Leski Tomasz A, Lamin Joseph M, Lahai Joseph, Bangura Umaru, Bockarie Alfred S, Taitt Chris R, Yasuda Chadwick, Bockarie Moses J, Stenger David A
机构信息
Mercy Hospital Research Laboratory, Kulanda Town, Bo, Sierra Leone.
Department of Community Health and Clinical Studies, Njala University, Bo, Sierra Leone.
出版信息
BMC Res Notes. 2018 Feb 8;11(1):113. doi: 10.1186/s13104-018-3218-8.
OBJECTIVE
The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg) among febrile individuals tested at Mercy Hospital Research Laboratory (MHRL) in Bo, Sierra Leone.
RESULTS
A total of 860 febrile individuals ages 5 years and older were tested by MHRL between July 2012 and June 2013 with a Standard Diagnostics Bioline HBsAg rapid diagnostic test. The overall HBsAg prevalence rate was 13.7%, including a rate of 15.5% among males and 12.6% among females. The HBsAg rate did not differ by child or adult age group (p > 0.5). The prevalence rate in Bo was similar to the 11-15% HBsAg prevalence rates reported in the past decade from other studies across West Africa. Scaling up the infant hepatitis B vaccination program in Sierra Leone will be important for reducing the future burden of disease and premature death attributable to chronic viral hepatitis B disease.
目的
本研究旨在确定在塞拉利昂博城的慈悲医院研究实验室（MHRL）接受检测的发热患者中乙肝表面抗原（HBsAg）的流行率。
结果
2012年7月至2013年6月期间，MHRL使用标准诊断生物线HBsAg快速诊断检测法对总共860名5岁及以上的发热患者进行了检测。HBsAg总体流行率为13.7%，其中男性为15.5%，女性为12.6%。HBsAg率在儿童或成人年龄组之间没有差异（p>0.5）。博城的流行率与过去十年西非其他研究报告的11%-15%的HBsAg流行率相似。扩大塞拉利昂的婴儿乙肝疫苗接种计划对于减轻未来由慢性乙型病毒性肝炎疾病导致的疾病负担和过早死亡至关重要。
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