Tiller Nicholas B, Simpson Andrew J
Academy of Sport and Physical Activity, Sheffield Hallam University, Sheffield, S10 2BP, UK.
Centre for Human Performance, Exercise and Rehabilitation, Brunel University, London, UK.
BMC Res Notes. 2018 Feb 8;11(1):110. doi: 10.1186/s13104-018-3217-9.
Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, recreationally-active men performed spirometry while oesophageal pressure was recorded using a latex balloon-tipped catheter.
Peak oesophageal pressure during inspiration was - 47 ± 9 cmHO (37 ± 10% of maximal inspiratory pressure), while peak oesophageal pressure during forced expiration was 102 ± 34 cmHO (75 ± 17% of maximal expiratory pressure). The deleterious consequences of spirometry might be associated with intra-thoracic pressures that approach maximal values during forced expiration.
由于用力肺活量动作会产生较高的胸内压，肺活量测定法不适用于脆弱患者。然而，尚未有关于肺活量测定法典型压力反应的报道。八名健康、有运动习惯的男性进行肺活量测定，同时使用带乳胶气囊的导管记录食管压力。
吸气时食管峰值压力为-47±9cmH₂O（最大吸气压力的37±10%），而用力呼气时食管峰值压力为102±34cmH₂O（最大呼气压力的75±17%）。肺活量测定法的有害后果可能与用力呼气时接近最大值的胸内压有关。
