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[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.

机构信息

Medical Care Branch of Panjin Vocational and Technical College, Panjin, P.R. China.

Department of Surgical Oncology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, P.R. China.

出版信息

Oncol Res. 2018 Dec 27;27(1):9-17. doi: 10.3727/096504018X15178732625479. Epub 2018 Feb 8.

DOI:10.3727/096504018X15178732625479

PMID:29422112

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7848419/

Abstract

THIS ARTICLE WAS WITHDRAWN BY THE PUBLISHERS IN NOVEMBER 2020.

摘要

本文已于 2020 年 11 月被出版商撤回。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/863a/7848419/c982ff2df990/OR-27-009-g001.jpg

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[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

Oncol Res. 2018 Dec 27;27(1):9-17. doi: 10.3727/096504018X15178732625479. Epub 2018 Feb 8.

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MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2.MicroRNA-506 通过下调 LHX2 抑制 Wnt/β-catenin 信号通路抑制鼻咽癌的肿瘤生长和转移。

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MiR-675 is frequently overexpressed in gastric cancer and enhances cell proliferation and invasion via targeting a potent anti-tumor gene PITX1.miR-675 在胃癌中经常过表达，通过靶向一种有效的抗肿瘤基因 PITX1 促进细胞增殖和侵袭。

Cell Signal. 2019 Oct;62:109352. doi: 10.1016/j.cellsig.2019.109352. Epub 2019 Jun 28.

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Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.NCAPG 的过表达通过 Wnt/β-catenin 信号通路抑制贲门腺癌细胞凋亡并促进上皮间质转化。

Gene. 2021 Jan 15;766:145163. doi: 10.1016/j.gene.2020.145163. Epub 2020 Sep 24.

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Tumor Inhibitory Effect of Long Non-coding RNA LOC100505817 on Gastric Cancer.长链非编码 RNA LOC100505817 对胃癌的抑制作用。

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SUFU mediates EMT and Wnt/β-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer.SUFU 介导 miRNA-324-5p 促进的人胃癌 EMT 和 Wnt/β-连环蛋白信号通路的激活。

Cell Cycle. 2020 Oct;19(20):2720-2733. doi: 10.1080/15384101.2020.1826632. Epub 2020 Oct 5.

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Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.下调的 microRNA-200a 通过靶向胃腺癌中的 E-钙黏蛋白抑制剂 ZEB1/ZEB2，通过 wnt/β-连环蛋白通路促进 EMT 和肿瘤生长。

Oncol Rep. 2013 Apr;29(4):1579-87. doi: 10.3892/or.2013.2267. Epub 2013 Jan 31.

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Label-Free Quantitative Proteomics Combined with Biological Validation Reveals Activation of Wnt/β-Catenin Pathway Contributing to Trastuzumab Resistance in Gastric Cancer.无标记定量蛋白质组学联合生物学验证揭示 Wnt/β-连环蛋白通路的激活导致胃癌对曲妥珠单抗耐药。

Int J Mol Sci. 2018 Jul 6;19(7):1981. doi: 10.3390/ijms19071981.

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SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway.丝氨酸蛋白酶抑制剂家族 H1 蛋白通过 Wnt/β-连环蛋白信号通路调控 EMT 及胃癌转移。

Aging (Albany NY). 2020 Feb 24;12(4):3574-3593. doi: 10.18632/aging.102831.

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miR-375-3p/YWHAZ/β-catenin axis regulates migration, invasion, EMT in gastric cancer cells.miR-375-3p/YWHAZ/β-catenin 轴调控胃癌细胞的迁移、侵袭和 EMT。

Clin Exp Pharmacol Physiol. 2019 Feb;46(2):144-152. doi: 10.1111/1440-1681.13047. Epub 2018 Dec 21.

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CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions.CagA 和 VacA 抑制胃黏膜上皮细胞自噬，促进胃癌前病变的进展。

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jul 28;47(7):942-951. doi: 10.11817/j.issn.1672-7347.2022.210779.

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MicroRNAs in Epithelial-Mesenchymal Transition Process of Cancer: Potential Targets for Chemotherapy.微小 RNA 在癌症上皮间质转化过程中的作用：化疗的潜在靶点。

Int J Mol Sci. 2021 Jul 14;22(14):7526. doi: 10.3390/ijms22147526.

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Expression of Wnt3, βcatenin and MMP7 in gastric cancer and precancerous lesions and their correlations with infection.

本文引用的文献

1

MiR-630 inhibits invasion and metastasis in esophageal squamous cell carcinoma.微小RNA-630抑制食管鳞状细胞癌的侵袭和转移。

Acta Biochim Biophys Sin (Shanghai). 2016 Sep;48(9):810-9. doi: 10.1093/abbs/gmw073. Epub 2016 Aug 25.

2

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1.结直肠癌中ZFP36表达缺失与Wnt/β-连环蛋白活性相关，并通过上调ZEB1、SOX9和MACC1增强上皮-间质转化。

Oncotarget. 2016 Sep 13;7(37):59144-59157. doi: 10.18632/oncotarget.10828.

3

LncRNA UCA1 promotes epithelial-mesenchymal transition (EMT) of breast cancer cells via enhancing Wnt/beta-catenin signaling pathway.

[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.

机构信息

Medical Care Branch of Panjin Vocational and Technical College, Panjin, P.R. China.

Department of Surgical Oncology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, P.R. China.

出版信息

Oncol Res. 2018 Dec 27;27(1):9-17. doi: 10.3727/096504018X15178732625479. Epub 2018 Feb 8.

DOI:10.3727/096504018X15178732625479

PMID:29422112

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7848419/

Abstract

THIS ARTICLE WAS WITHDRAWN BY THE PUBLISHERS IN NOVEMBER 2020.

摘要

本文已于 2020 年 11 月被出版商撤回。

相似文献

1

[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

Oncol Res. 2018 Dec 27;27(1):9-17. doi: 10.3727/096504018X15178732625479. Epub 2018 Feb 8.

2

MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2.MicroRNA-506 通过下调 LHX2 抑制 Wnt/β-catenin 信号通路抑制鼻咽癌的肿瘤生长和转移。

J Exp Clin Cancer Res. 2019 Feb 21;38(1):97. doi: 10.1186/s13046-019-1023-4.

3

MiR-675 is frequently overexpressed in gastric cancer and enhances cell proliferation and invasion via targeting a potent anti-tumor gene PITX1.miR-675 在胃癌中经常过表达，通过靶向一种有效的抗肿瘤基因 PITX1 促进细胞增殖和侵袭。

Cell Signal. 2019 Oct;62:109352. doi: 10.1016/j.cellsig.2019.109352. Epub 2019 Jun 28.

4

Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.NCAPG 的过表达通过 Wnt/β-catenin 信号通路抑制贲门腺癌细胞凋亡并促进上皮间质转化。

Gene. 2021 Jan 15;766:145163. doi: 10.1016/j.gene.2020.145163. Epub 2020 Sep 24.

5

Tumor Inhibitory Effect of Long Non-coding RNA LOC100505817 on Gastric Cancer.长链非编码 RNA LOC100505817 对胃癌的抑制作用。

Pathol Oncol Res. 2021 May 26;27:581542. doi: 10.3389/pore.2021.581542. eCollection 2021.

6

SUFU mediates EMT and Wnt/β-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer.SUFU 介导 miRNA-324-5p 促进的人胃癌 EMT 和 Wnt/β-连环蛋白信号通路的激活。

Cell Cycle. 2020 Oct;19(20):2720-2733. doi: 10.1080/15384101.2020.1826632. Epub 2020 Oct 5.

7

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.下调的 microRNA-200a 通过靶向胃腺癌中的 E-钙黏蛋白抑制剂 ZEB1/ZEB2，通过 wnt/β-连环蛋白通路促进 EMT 和肿瘤生长。

Oncol Rep. 2013 Apr;29(4):1579-87. doi: 10.3892/or.2013.2267. Epub 2013 Jan 31.

8

Label-Free Quantitative Proteomics Combined with Biological Validation Reveals Activation of Wnt/β-Catenin Pathway Contributing to Trastuzumab Resistance in Gastric Cancer.无标记定量蛋白质组学联合生物学验证揭示 Wnt/β-连环蛋白通路的激活导致胃癌对曲妥珠单抗耐药。

Int J Mol Sci. 2018 Jul 6;19(7):1981. doi: 10.3390/ijms19071981.

9

SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway.丝氨酸蛋白酶抑制剂家族 H1 蛋白通过 Wnt/β-连环蛋白信号通路调控 EMT 及胃癌转移。

Aging (Albany NY). 2020 Feb 24;12(4):3574-3593. doi: 10.18632/aging.102831.

10

miR-375-3p/YWHAZ/β-catenin axis regulates migration, invasion, EMT in gastric cancer cells.miR-375-3p/YWHAZ/β-catenin 轴调控胃癌细胞的迁移、侵袭和 EMT。

Clin Exp Pharmacol Physiol. 2019 Feb;46(2):144-152. doi: 10.1111/1440-1681.13047. Epub 2018 Dec 21.

引用本文的文献

1

CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions.CagA 和 VacA 抑制胃黏膜上皮细胞自噬，促进胃癌前病变的进展。

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jul 28;47(7):942-951. doi: 10.11817/j.issn.1672-7347.2022.210779.

2

MicroRNAs in Epithelial-Mesenchymal Transition Process of Cancer: Potential Targets for Chemotherapy.微小 RNA 在癌症上皮间质转化过程中的作用：化疗的潜在靶点。

Int J Mol Sci. 2021 Jul 14;22(14):7526. doi: 10.3390/ijms22147526.

3

Expression of Wnt3, βcatenin and MMP7 in gastric cancer and precancerous lesions and their correlations with infection.

本文引用的文献

1

MiR-630 inhibits invasion and metastasis in esophageal squamous cell carcinoma.微小RNA-630抑制食管鳞状细胞癌的侵袭和转移。

Acta Biochim Biophys Sin (Shanghai). 2016 Sep;48(9):810-9. doi: 10.1093/abbs/gmw073. Epub 2016 Aug 25.

2

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1.结直肠癌中ZFP36表达缺失与Wnt/β-连环蛋白活性相关，并通过上调ZEB1、SOX9和MACC1增强上皮-间质转化。

Oncotarget. 2016 Sep 13;7(37):59144-59157. doi: 10.18632/oncotarget.10828.

3

LncRNA UCA1 promotes epithelial-mesenchymal transition (EMT) of breast cancer cells via enhancing Wnt/beta-catenin signaling pathway.

Wnt3、β-catenin 和 MMP7 在胃癌及癌前病变中的表达及其与感染的相关性

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Jun 28;46(6):575-582. doi: 10.11817/j.issn.1672-7347.2021.200733.

4

miR‑576‑5p promotes epithelial‑to‑mesenchymal transition in colorectal cancer by targeting the Wnt5a‑mediated Wnt/β‑catenin signaling pathway.miR-576-5p 通过靶向 Wnt5a 介导的 Wnt/β-连环蛋白信号通路促进结直肠癌细胞上皮-间充质转化。

Mol Med Rep. 2021 Feb;23(2). doi: 10.3892/mmr.2020.11733. Epub 2020 Dec 10.

5

High-throughput microRNA profile in adult and pediatric primary glioblastomas: the role of miR-10b-5p and miR-630 in the tumor aggressiveness.成人和儿童原发性神经胶质瘤中的高通量 microRNA 谱：miR-10b-5p 和 miR-630 在肿瘤侵袭性中的作用。

Mol Biol Rep. 2020 Sep;47(9):6949-6959. doi: 10.1007/s11033-020-05754-3. Epub 2020 Sep 4.

6

MicroRNAs target the Wnt/β‑catenin signaling pathway to regulate epithelial‑mesenchymal transition in cancer (Review).微小 RNA 靶向 Wnt/β-连环蛋白信号通路调控癌症中的上皮-间充质转化（综述）。

Oncol Rep. 2020 Oct;44(4):1299-1313. doi: 10.3892/or.2020.7703. Epub 2020 Jul 23.

7

miR-665 Suppresses the Epithelial-Mesenchymal Transition and Progression of Gastric Cancer by Targeting .微小RNA-665通过靶向作用抑制胃癌的上皮-间质转化及进展。（注：原文中“Targeting”后缺少具体内容）

Cancer Manag Res. 2020 May 15;12:3489-3501. doi: 10.2147/CMAR.S241795. eCollection 2020.

8

miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3.miR-378a-5p 和 miR-630 通过抑制 E2F3 诱导白内障晶状体上皮细胞凋亡。

Braz J Med Biol Res. 2020;53(5):e9608. doi: 10.1590/1414-431x20209608. Epub 2020 Apr 27.

9

lncRNA SNHG7 sponges miR-425 to promote proliferation, migration, and invasion of hepatic carcinoma cells via Wnt/β-catenin/EMT signalling pathway.lncRNA SNHG7 通过海绵吸附 miR-425 促进肝癌细胞增殖、迁移和侵袭，并激活 Wnt/β-catenin/EMT 信号通路。

Cell Biochem Funct. 2019 Oct;37(7):525-533. doi: 10.1002/cbf.3429. Epub 2019 Sep 2.

长链非编码RNA UCA1通过增强Wnt/β-连环蛋白信号通路促进乳腺癌细胞的上皮-间质转化（EMT）。

Eur Rev Med Pharmacol Sci. 2016 Jul;20(13):2819-24.

4

MicroRNA-630 suppresses tumor metastasis through the TGF-β- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma.微小RNA-630通过TGF-β-微小RNA-630-Slug信号通路抑制肿瘤转移，且与肝细胞癌的不良预后呈负相关。

Oncotarget. 2016 Apr 19;7(16):22674-86. doi: 10.18632/oncotarget.8047.

5

Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells.Wnt/β-连环蛋白信号通路在CXCL12过表达的乳腺癌细胞上皮-间质转化过程中是必需的。

Int J Clin Exp Pathol. 2015 Oct 1;8(10):12357-67. eCollection 2015.

6

LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling.LGR5通过激活Wnt/β-连环蛋白信号通路促进乳腺癌进展并维持干细胞样细胞。

Stem Cells. 2015 Oct;33(10):2913-24. doi: 10.1002/stem.2083. Epub 2015 Jul 14.

7

Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial-mesenchymal transition in cancer.微小RNA与WNT/β-连环蛋白信号通路之间的相互作用调节癌症中的上皮-间质转化。

Eur J Cancer. 2015 Aug;51(12):1638-49. doi: 10.1016/j.ejca.2015.04.021. Epub 2015 May 26.

8

Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.全球癌症发病与死亡：GLOBOCAN 2012 数据源、方法与主要模式。

Int J Cancer. 2015 Mar 1;136(5):E359-86. doi: 10.1002/ijc.29210. Epub 2014 Oct 9.

9

Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.胃癌：描述性流行病学、风险因素、筛查与预防

Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):700-13. doi: 10.1158/1055-9965.EPI-13-1057. Epub 2014 Mar 11.

10

Molecular mechanisms of epithelial-mesenchymal transition.上皮-间质转化的分子机制。

Nat Rev Mol Cell Biol. 2014 Mar;15(3):178-96. doi: 10.1038/nrm3758.

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[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.

机构信息

出版信息

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本文引用的文献

[文章撤回] miR-630 通过调控胃癌细胞中的 Wnt/β-连环蛋白通路抑制上皮间质转化（EMT）。

[ARTICLE WITHDRAWN] miR-630 Inhibits Epithelial-to-Mesenchymal Transition (EMT) by Regulating the Wnt/β-Catenin Pathway in Gastric Cancer Cells.

机构信息

出版信息

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