NeurObesity Group, Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, 15782 Santiago de Compostela, Spain; CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn), 15706 Santiago de Compostela, Spain.
Trends Endocrinol Metab. 2018 Mar;29(3):135-137. doi: 10.1016/j.tem.2018.01.004.
Hypothalamic AMP-activated protein kinase (AMPK) is an important modulator of whole-body energy homeostasis, particularly within the ventromedial nucleus, where it regulates energy expenditure, glucose, and lipid metabolism. A recent paper in Cell Reports has demonstrated that AMPK in the paraventricular nucleus of the hypothalamus modulates dietary preference for carbohydrate over fat.
下丘脑的 AMP 激活的蛋白激酶（AMPK）是全身能量稳态的重要调节剂，特别是在腹内侧核中，它调节能量消耗、葡萄糖和脂质代谢。最近在《细胞报告》上的一篇论文表明，下丘脑室旁核中的 AMPK 调节了对碳水化合物而非脂肪的饮食偏好。
