急性中心性浆液性脉络膜视网膜病变中对比敏感度变化模式
Pattern of Contrast Sensitivity Changes in Acute Central Serous Chorioretinopathy.
作者信息
Lourthai Preeyachan, Bhurayanontachai Patama
机构信息
Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
出版信息
J Ophthalmol. 2017;2017:9053932. doi: 10.1155/2017/9053932. Epub 2017 Dec 20.
PURPOSE
To evaluate contrast sensitivity (CS) changes in acute central serous chorioretinopathy (CSC).
METHODS
Visual acuity (VA), CS, and subretinal fluid (SRF) were evaluated monthly for 6 months. Treatment was considered at 3 months in case of persistent SRF.
RESULTS
Twelve of 20 eyes (60%) had spontaneous SRF resolution within 4 months. Five of 8 patients with delayed SRF resolution received either focal laser or photodynamic therapy. The CS was impaired in all spatial frequencies at baseline. There was a negative correlation between the baseline SRF thickness and CS at 3 and 6 cycles per degree (cpd). The CS improved significantly at the time of fluid resolution ( = 0.001) and continued to improve in 3 and 6 cpd. The CS at 6 cpd did not recover if compared to a normal fellow eye at 6 months ( = 0.018). The CS of 12 cpd at 6 months was superior in the spontaneous resolution group.
CONCLUSION
The impaired CS gradually improved as the SRF reduced at all spatial frequencies. CS at 3 and 12 cpd continued to improve after complete fluid resolution. Despite an excellent final VA, the CS at 6 months did not regain its normal value.
目的
评估急性中心性浆液性脉络膜视网膜病变（CSC）患者的对比敏感度（CS）变化。
方法
连续6个月每月评估视力（VA）、CS和视网膜下液（SRF）。若SRF持续存在，则在3个月时考虑进行治疗。
结果
20只眼中有12只眼（60%）在4个月内视网膜下液自发消退。8例视网膜下液消退延迟的患者中有5例接受了局部激光或光动力疗法。所有空间频率的CS在基线时均受损。基线时视网膜下液厚度与每度3和6周波（cpd）时的CS呈负相关。视网膜下液消退时CS显著改善（P = 0.001），在3和6 cpd时继续改善。与正常对侧眼相比，6个月时6 cpd的CS未恢复（P = 0.018）。自发消退组6个月时12 cpd的CS较好。
结论
随着视网膜下液在所有空间频率上减少，受损的CS逐渐改善。完全消退后，3和cpd的CS继续改善。尽管最终视力良好，但6个月时的CS未恢复到正常水平。
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