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中心性浆液性脉络膜视网膜病变患者经黄斑阈下激光治疗后视力和对比敏感度的改善。

Improvement in visual acuity and contrast sensitivity in patients with central serous chorioretinopathy after macular subthreshold laser therapy.

机构信息

Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.

出版信息

Retina. 2013 Feb;33(2):324-8. doi: 10.1097/IAE.0b013e3182670fa3.

Abstract

PURPOSE

The purpose of the study was to measure the improvement in vision and contrast sensitivity in patients with central serous chorioretinopathy after macular subthreshold laser therapy.

METHODS

Cases included in this clinical trial were patients diagnosed with acute central serous chorioretinopathy less than 1 month in duration. Each patient was randomized to either observation group or treatment group with subthreshold argon laser. First and sixth month of follow-up results were then recorded, and visual improvement and contrast sensitivity were compared between the two groups.

RESULTS

Of 37 patients with central serous chorioretinopathy, 25 were men and 12 were women with a mean age of 38.6 ± 5.9 years. At 6 months, mean best-corrected visual acuity improved from 0.26 to 0.03 logarithm of the minimum angle of resolution in the laser group and from 0.12 to 0.04 logarithm of the minimum angle of resolution in the observation group (P < 0.001). Except spatial frequencies of 18 cycles per degree (P = 0.207), the contrast sensitivity in spatial frequencies of 3, 6, and 12 cycles per degree was significantly more favorable in the laser group during the first and sixth month.

CONCLUSION

Treatment of patients with acute central serous chorioretinopathy with subthreshold laser improved the best-corrected visual acuity and contrast sensitivity compared with those in the observation group. The laser group also showed a more rapid improvement. In both groups, best-corrected visual acuity improved in most patients after 6 months; however, the contrast sensitivity was significantly better in the treatment group.

摘要

目的

本研究旨在测量接受黄斑阈下激光治疗的中心性浆液性脉络膜视网膜病变患者视力和对比敏感度的改善情况。

方法

本临床试验纳入的病例为病程在 1 个月以内的急性中心性浆液性脉络膜视网膜病变患者。将每位患者随机分为观察组和阈下氩激光治疗组。然后记录第 1 个月和第 6 个月的随访结果,并比较两组的视力改善和对比敏感度。

结果

37 例中心性浆液性脉络膜视网膜病变患者中,男性 25 例,女性 12 例,平均年龄 38.6 ± 5.9 岁。6 个月时,激光组的最佳矫正视力从 0.26 提高至 0.03 对数最小角分辨率,观察组从 0.12 提高至 0.04 对数最小角分辨率(P<0.001)。除 18 周/度空间频率外(P=0.207),激光组在第 1 个月和第 6 个月的 3、6 和 12 周/度空间频率的对比敏感度均明显更优。

结论

与观察组相比,阈下激光治疗急性中心性浆液性脉络膜视网膜病变患者可提高最佳矫正视力和对比敏感度,且激光组的改善速度更快。两组患者在 6 个月后多数患者的最佳矫正视力都有所提高,但治疗组的对比敏感度明显更好。

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