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肩人工关节置换术后假体周围关节感染:诊断和治疗选择。

Periprosthetic Joint Infection of Shoulder Arthroplasties: Diagnostic and Treatment Options.

机构信息

Department of Joint Replacement, General and Rheumatic Orthopaedics, Orthopaedic Clinic Markgröningen gGmbH, Kurt-Lindemann-Weg 10, 71706 Markgröningen, Germany.

Orthopaedic Department, University-Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

出版信息

Biomed Res Int. 2017;2017:4582756. doi: 10.1155/2017/4582756. Epub 2017 Dec 20.

Abstract

Periprosthetic joint infection (PJI) is one of the most frequent reasons for painful shoulder arthroplasties and revision surgery of shoulder arthroplasties. is one of the microorganisms that most often causes the infection. However, this slow growing microorganism is difficult to detect. This paper presents an overview of different diagnostic test to detect a periprosthetic shoulder infection. This includes nonspecific diagnostic tests and specific tests (with identifying the responsible microorganism). The aspiration can combine different specific and nonspecific tests. In dry aspiration and suspected joint infection, we recommend a biopsy. Several therapeutic options exist for the treatment of PJI of shoulder arthroplasties. In acute infections, the options include leaving the implant in place with open debridement, septic irrigation with antibacterial fluids like octenidine or polyhexanide solution, and exchange of all removable components. In late infections (more than four weeks after implantation) the therapeutic options are a permanent spacer, single-stage revision, and two-stage revision with a temporary spacer. The functional results are best after single-stage revisions with a success rate similar to two-stage revisions. For single-stage revisions, the microorganism should be known preoperatively so that specific antibiotics can be mixed into the cement for implantation of the new prosthesis and specific systemic antibiotic therapy can be applied to support the surgery.

摘要

人工关节周围感染(PJI)是导致肩部人工关节疼痛和翻修手术的最常见原因之一。 是最常引起感染的微生物之一。然而,这种生长缓慢的微生物很难被检测到。本文概述了不同的诊断试验来检测人工肩关节感染。这包括非特异性诊断试验和特异性试验(确定引起感染的微生物)。抽吸可以结合不同的特异性和非特异性试验。在干燥抽吸和疑似关节感染时,我们建议进行活检。对于人工肩关节置换术后 PJI 的治疗,存在多种治疗选择。在急性感染中,选择包括在开放性清创术时保留植入物、用抗菌液(如奥替尼啶或聚己双胍溶液)进行感染冲洗,以及更换所有可移动部件。在晚期感染(植入后超过四周),治疗选择包括永久性间隔器、单阶段翻修和带临时间隔器的两阶段翻修。单阶段翻修的功能结果最好,成功率与两阶段翻修相似。对于单阶段翻修,应在术前了解微生物,以便将特定抗生素混入新假体的水泥中,并进行特定的全身抗生素治疗以支持手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd6f/5750516/39e52f176164/BMRI2017-4582756.001.jpg

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