Head of Movement Disorders Section, Department of Neurology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Chulalongkorn Centre for Excellence on Parkinson's Disease and Related Disorders, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
J Neurol. 2018 Apr;265(4):856-862. doi: 10.1007/s00415-018-8759-1. Epub 2018 Feb 8.
Spasticity is a symptom occurring in many neurological conditions including stroke, multiple sclerosis, hypoxic brain damage, traumatic brain injury, tumours and heredodegenerative diseases. It affects large numbers of patients and may cause major disability. So far, spasticity has merely been described as part of the upper motor neurone syndrome or defined in a narrowed neurophysiological sense. This consensus organised by IAB-Interdisciplinary Working Group Movement Disorders wants to provide a brief and practical new definition of spasticity-for the first time-based on its various forms of muscle hyperactivity as described in the current movement disorders terminology. We propose the following new definition system: Spasticity describes involuntary muscle hyperactivity in the presence of central paresis. The involuntary muscle hyperactivity can consist of various forms of muscle hyperactivity: spasticity sensu strictu describes involuntary muscle hyperactivity triggered by rapid passive joint movements, rigidity involuntary muscle hyperactivity triggered by slow passive joint movements, dystonia spontaneous involuntary muscle hyperactivity and spasms complex involuntary movements usually triggered by sensory or acoustic stimuli. Spasticity can be described by a documentation system grouped along clinical picture (axis 1), aetiology (axis 2), localisation (axis 3) and additional central nervous system deficits (axis 4). Our new definition allows distinction of spasticity components accessible to BT therapy and those inaccessible. The documentation sheet presented provides essential information for planning of BT therapy.
痉挛是一种在许多神经系统疾病中出现的症状,包括中风、多发性硬化症、缺氧性脑损伤、创伤性脑损伤、肿瘤和遗传性退行性疾病。它影响了大量的患者,并可能导致严重的残疾。到目前为止,痉挛只是被描述为上运动神经元综合征的一部分,或者在狭义的神经生理学意义上被定义。由 IAB-跨学科工作组运动障碍组织的这项共识旨在提供一个简短而实用的痉挛新定义-这是第一次基于当前运动障碍术语中描述的各种肌肉过度活动形式。我们提出了以下新的定义系统:痉挛描述了在中枢性瘫痪存在的情况下的不随意肌肉过度活动。不随意肌肉过度活动可以包括各种形式的肌肉过度活动:痉挛严格意义上描述了由快速被动关节运动触发的不随意肌肉过度活动,僵硬描述了由缓慢被动关节运动触发的不随意肌肉过度活动,肌张力障碍描述了自发性不随意肌肉过度活动,痉挛是一种复杂的不随意运动,通常由感觉或听觉刺激触发。痉挛可以通过一个沿着临床表现(轴 1)、病因(轴 2)、定位(轴 3)和额外的中枢神经系统缺陷(轴 4)分组的文档系统来描述。我们的新定义允许区分可接受 BT 治疗的痉挛成分和不可接受的痉挛成分。所提出的文档表提供了 BT 治疗计划的重要信息。