Torretta S, Marchisio P, Rinaldi V, Carioli D, Nazzari E, Pignataro L
ENT Unit, Department of Clinical Scinces and Community Health, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Highly Intensive Pediatric Care Unit, Department of Pathophysiology and Transplantations, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Eur Arch Otorhinolaryngol. 2018 Mar;275(3):829-830. doi: 10.1007/s00405-018-4896-5. Epub 2018 Feb 8.
Some considerations will be expressed in consideration of the commentary previously published. In particular, we underline that no other medications were administered to the patients during the study period and any clinical evaluation was postponed in case of acute upper respiratory tract infection in the previous 14 days. We strongly advocate antibiotic treatment during any acute otitis media episode, and we agree that topically administered hyaluronic acid should be considered as a supporting treatment, "complementary to traditional therapies" in children with recurrent disease.
考虑到之前发表的评论，将阐述一些观点。特别要强调的是，在研究期间未给患者使用其他药物，并且如果患者在过去14天内患有急性上呼吸道感染，则任何临床评估都将推迟。我们强烈主张在任何急性中耳炎发作期间进行抗生素治疗，并且我们同意，对于复发性疾病的儿童，局部应用透明质酸应被视为一种辅助治疗，“作为传统疗法的补充”。
