Sherlock S
Dig Dis Sci. 1986 Sep;31(9 Suppl):122S-132S. doi: 10.1007/BF01295994.
Developments over the last four years in our understanding of viral hepatitis are analyzed. The molecular structure of hepatitis A has been established, and vaccines for prevention are under development. The recognition of the replicative and integrated stages of hepatitis B infection has allowed more rational approaches to therapy. Vaccines are of proven value. Delta virus infection has assumed an important role world wide as a cause of serious and fulminant liver disease in hepatitis B carriers. The agents for non-A, non-B virus hepatitis have eluded identification. These are important causes of chronic liver disease particularly in recipients of blood transfusion.
分析了过去四年中我们对病毒性肝炎认识的进展。甲型肝炎的分子结构已确定，预防疫苗正在研制中。对乙型肝炎感染复制和整合阶段的认识使治疗方法更加合理。疫苗已被证明有价值。丁型肝炎病毒感染作为乙型肝炎携带者严重和暴发性肝病的病因在全球已占据重要地位。非甲非乙型肝炎的病原体仍未确定。这些是慢性肝病的重要病因，尤其是在输血受者中。
