Zago Daniane C, Santos Alessandro C, Lanes Carlos F C, Almeida Daniela V, Koakoski Gessi, de Abreu Murilo S, Zeppenfeld Carla C, Heinzmann Berta M, Marins Luis F, Baldisserotto Bernardo, Barcellos Leonardo J G, Cunha Mauro A
Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, UFSM, Av. Roraima, 1000, Santa Maria, RS, 97105-900, Brazil.
Universidade Federal do Pampa, Campus Uruguaiana, BR 472, Km 592, Caixa Postal 118, Uruguaiana, RS, 97508-000, Brazil.
Fish Physiol Biochem. 2018 Apr;44(2):465-474. doi: 10.1007/s10695-017-0446-0. Epub 2018 Feb 8.
Dietary supplements are commonly used by animals and humans and play key roles in diverse systems, such as the immune and reproductive systems, and in metabolism. Essential oils (EOs), which are natural substances, have potential for use in food supplementation; however, their effects on organisms remain to be elucidated. Here, we examine the effects of dietary Aloysia triphylla EO supplementation on zebrafish behavior, metabolism, stress response, and growth performance. We show that fish fed diets containing A. triphylla EO presented an anxiolytic response, with reduced exploratory activity and oxygen consumption; no changes were observed in neuroendocrine stress axis functioning and growth was not impaired. Taken together, these results suggest that the A. triphylla EO supplementation is a strong candidate for use in feed, since it ensures fish welfare (anxiolytic behavior) with decreased oxygen consumption. This makes it suitable for use in high-density production systems without causing damage to the neuroendocrine stress axis and without growth performance being impaired.
膳食补充剂在动物和人类中普遍使用，并在多种系统中发挥关键作用，如免疫系统、生殖系统和新陈代谢。精油（EOs）作为天然物质，具有用于食品补充的潜力；然而，它们对生物体的影响仍有待阐明。在此，我们研究了膳食添加三叶轮钟草精油对斑马鱼行为、新陈代谢、应激反应和生长性能的影响。我们发现，喂食含有三叶轮钟草精油饲料的鱼表现出抗焦虑反应，探索活动和耗氧量减少；神经内分泌应激轴功能未观察到变化，生长也未受到损害。综上所述，这些结果表明，添加三叶轮钟草精油是饲料使用的有力候选者，因为它能确保鱼类健康（抗焦虑行为）并降低耗氧量。这使其适用于高密度生产系统，而不会对神经内分泌应激轴造成损害，也不会损害生长性能。
