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基于 3 型非中心睡眠试验的日本医学生睡眠障碍呼吸的流行率。

Prevalence of sleep-disordered breathing in Japanese medical students based on type-3 out-of-center sleep test.

机构信息

Division of Behavioral Sleep Medicine, Iwate Medical University School of Medicine, Morioka, Japan.

Division of Behavioral Sleep Medicine, Iwate Medical University School of Medicine, Morioka, Japan.

出版信息

Sleep Med. 2018 Jan;41:9-14. doi: 10.1016/j.sleep.2017.09.023. Epub 2017 Oct 12.

DOI:10.1016/j.sleep.2017.09.023
PMID:29425583
Abstract

BACKGROUND

Sleep-disordered breathing (SDB), especially obstructive sleep apnea disorder (OSA), is thought to mainly affect men over the age of 40. Following findings that Asian people are more likely to experience severe OSA, regardless of obesity, we investigated the prevalence of SDB and OSA in a larger sample and in more younger age groups than those described in previous reports.

METHODS

Between 2011 and 2016, 487 medical students (358 males, mean age 24.8 ± 1.9 years; 129 females: mean age 23.8 ± 1.6 years) underwent an out-of-center sleep test using a type-3 portable monitor. The results were analyzed visually.

RESULTS

The mean ± standard deviation of the respiratory event index (REI: events/hour of monitoring) was 5.4 ± 6.7 (6.7 ± 7.5 in male participants, 2.6 ± 2.1 in female participants). There were 170 participants (36.6%) with an REI≥5, including 158 male participants (46.9%) and 12 female participants (9.1%). SDB or undefined OSA with low REI (15 > REI≥5) was observed in 141 participants (30.4%), defined OSA with moderate REI (30 > REI≥15) in 19 participants (4.1%), and defined OSA with high REI (REI≥30) in 10 participants (2.2%). Among the male students, 129 had low REI (38.3%), 19 had moderate REI (5.6%), and 10 had high REI (3.0%). All female participants with OSA events (9.4%) had a low REI.

CONCLUSIONS

The prevalence of OSA in Japanese young adults, especially males under 30 years old, is similar or even higher than that in older age groups described previously. Thus, an aggressive sleep study for SDB might be necessary for the younger generation in the Asian population.

摘要

背景

睡眠呼吸障碍(SDB),特别是阻塞性睡眠呼吸暂停障碍(OSA),被认为主要影响 40 岁以上的男性。鉴于亚洲人无论肥胖与否,都更有可能经历严重的 OSA,我们在比以往报告更大的样本中,对更多年轻年龄组进行了 SDB 和 OSA 的流行情况调查。

方法

2011 年至 2016 年,487 名医学生(358 名男性,平均年龄 24.8±1.9 岁;129 名女性:平均年龄 23.8±1.6 岁)在中心外使用 3 型便携式监测仪进行睡眠测试。结果通过肉眼观察进行分析。

结果

呼吸事件指数(REI:每小时监测事件数)的平均值±标准差为 5.4±6.7(男性参与者为 6.7±7.5,女性参与者为 2.6±2.1)。有 170 名参与者(36.6%)的 REI≥5,其中包括 158 名男性参与者(46.9%)和 12 名女性参与者(9.1%)。有 141 名参与者(30.4%)患有 SDB 或低 REI 的未明确 OSA(15>REI≥5),19 名参与者(4.1%)患有中 REI 的明确 OSA(30>REI≥15),10 名参与者(2.2%)患有高 REI 的明确 OSA(REI≥30)。在男性学生中,129 名有低 REI(38.3%),19 名有中 REI(5.6%),10 名有高 REI(3.0%)。所有患有 OSA 事件的女性参与者(9.4%)的 REI 都较低。

结论

日本年轻成年人(尤其是 30 岁以下的男性)中 OSA 的患病率与之前描述的老年组相似甚至更高。因此,亚洲人群的年轻一代可能需要进行积极的 SDB 睡眠研究。

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