Department of Medicine, Huzhou University, Huzhou 313000, PR China.
Department of Medicine, Huzhou University, Huzhou 313000, PR China.
Int J Biol Macromol. 2018 Jun;112:796-802. doi: 10.1016/j.ijbiomac.2018.01.192. Epub 2018 Feb 8.
Effect of polysaccharides from two seaweeds, Porphyra haitanensis and Ulva prolifera, on intestinal microbiota in mice was evaluated by illumina PE250 sequencing. Analysis showed significant structural changes in fecal microbiota among the three sample groups. There were significant differences in the composition of fecal microbiota among the three groups at phylum and genus levels. At the phylum level, the most predominant phylum was Bacteroidetes contributing 58.76%, 73.39%, 75.38% and 64.40% of the fecal microbiota in K, Z, H and D groups respectively, followed by Firmicutes, contributing 37.61%, 23.99%, 21.87% and 30.82% respectively. Many genera were significantly higher in the Z and H group than in the K group, including Prevotellaceae UCG-001 (p<0.05) and Rikenellaceae RC9 (p<0.01). In conclusion, our results suggest that polysaccharide type and glycoside may contribute to shaping mice gut microbiota.
采用 Illumina PE250 测序技术评估两种海藻（紫菜和石莼）多糖对小鼠肠道微生物群的影响。分析显示，三组粪便样本的肠道微生物群结构存在显著差异。在门和属水平上，三组粪便微生物群的组成存在显著差异。在门水平上，最主要的菌门是拟杆菌门，分别占 K、Z、H 和 D 组粪便微生物群的 58.76%、73.39%、75.38%和 64.40%，其次是厚壁菌门，分别占 37.61%、23.99%、21.87%和 30.82%。Z 和 H 组的许多菌属明显高于 K 组，包括普雷沃氏菌科 UCG-001（p<0.05）和理研菌科 RC9（p<0.01）。综上所述，我们的结果表明，多糖类型和糖苷可能有助于塑造小鼠肠道微生物群。
