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首发精神分裂症谱系障碍患者的社会动机。

Social motivation in people with recent-onset schizophrenia spectrum disorders.

机构信息

San Francisco Veterans Affairs Medical Center, San Francisco, USA; Department of Psychiatry, University of California, San Francisco, USA.

Department of Psychiatry, University of California, San Francisco, USA.

出版信息

J Psychiatr Res. 2018 Apr;99:96-103. doi: 10.1016/j.jpsychires.2018.01.006. Epub 2018 Jan 12.

Abstract

People with schizophrenia-spectrum disorders (SSD) often experience impairments in non-social motivation. In this study, we extended this line of investigation by examining specific components of social motivation and the extent to which these components work together in people with and without a recent-onset SSD. Sixty-four people with a recent-onset SSD and 26 controls completed a task that allowed us to examine changes in anticipated pleasure, decisions to trust, and effort expenditure over the course of repeated interactions with positive or negative outcomes. Compared to controls, we found that people in the SSD group placed less trust, tended to anticipate less pleasure, and expended less effort to increase the likelihood of future interactions with positive outcomes. Further, in the SSD group, effort expenditure was not associated with either anticipated pleasure or decisions to trust. While there were no group differences in anticipated pleasure or trust placed during interactions with negative outcomes, people in the SSD group expended less effort to decrease to the likelihood of future interactions. Taken together, our findings suggest that people with a recent-onset SSD may experience both impairment and disconnection between various components of social motivation for interactions with positive outcomes. Implications for interventions for social engagement in people with SSD are discussed.

摘要

精神分裂症谱系障碍(SSD)患者通常存在非社交动机障碍。本研究通过考察社会动机的特定成分以及这些成分在 SSD 患者和无 SSD 患者中的协同作用程度,扩展了这一研究领域。64 名 SSD 患者和 26 名对照组参与者完成了一项任务,使我们能够在与积极或消极结果的反复互动过程中,观察预期愉悦感、信任决策和努力投入的变化。与对照组相比,我们发现 SSD 组的参与者信任程度较低,预期愉悦感较低,为增加未来与积极结果互动的可能性而付出的努力较少。此外,在 SSD 组中,努力投入与预期愉悦感或信任决策均无关联。虽然在与消极结果的互动过程中,参与者的预期愉悦感或信任程度没有组间差异,但 SSD 组为减少未来互动的可能性而付出的努力较少。总之,我们的研究结果表明,近期 SSD 患者在与积极结果的互动中,可能会出现社会动机的各种成分受损和脱节的情况。讨论了针对 SSD 患者社交参与的干预措施的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e62e/5849532/db4d9b71620b/nihms941614f1.jpg

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