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简要报告：自闭症谱系障碍儿童与其他发育迟缓及障碍儿童的自伤行为比较。

Brief Report: Self-Injurious Behaviors in Preschool Children with Autism Spectrum Disorder Compared to Other Developmental Delays and Disorders.

机构信息

Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.

National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS E-86, Atlanta, GA, 30341, USA.

出版信息

J Autism Dev Disord. 2018 Jul;48(7):2558-2566. doi: 10.1007/s10803-018-3490-4.

DOI:10.1007/s10803-018-3490-4
PMID:29429009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5997504/
Abstract

We compared the prevalence of self-injurious behaviors (SIB) in preschoolers aged 30-68 months with autism spectrum disorder (ASD) (n = 691) versus other developmental delays and disorders (DD) (n = 977) accounting for sociodemographic, cognitive, and medical factors. SIB prevalence was higher in ASD versus all DD [adjusted odds-ratio (aOR) 2.13 (95% confidence interval (95% CI) 1.53, 2.97)]. In subgroup analyses, SIB prevalence was higher in ASD versus DD without ASD symptoms [aOR 4.42 (95% CI 2.66, 7.33)], but was similar between ASD and DD with ASD symptoms [aOR 1.09 (95% CI 0.68, 1.77)]. We confirmed higher prevalence of SIB in ASD versus DD, independent of confounders. In children with DD, SIB prevalence increased with more ASD symptoms. These findings are informative to clinicians, researchers, and policymakers.

摘要

我们比较了 30-68 个月自闭症谱系障碍（ASD）（n=691）和其他发育迟缓障碍（DD）（n=977）学龄前儿童的自伤行为（SIB）的患病率，同时考虑了社会人口统计学、认知和医疗因素。与所有 DD 相比，ASD 中的 SIB 患病率更高[调整后的优势比（aOR）为 2.13（95%置信区间（95%CI）为 1.53，2.97）]。在亚组分析中，与无 ASD 症状的 DD 相比，ASD 中的 SIB 患病率更高[aOR 为 4.42（95%CI 为 2.66，7.33）]，但与有 ASD 症状的 DD 相比，ASD 中的 SIB 患病率相似[aOR 为 1.09（95%CI 为 0.68，1.77）]。我们证实了 ASD 中 SIB 的患病率高于 DD，且不受混杂因素的影响。在 DD 儿童中，SIB 的患病率随着 ASD 症状的增加而增加。这些发现为临床医生、研究人员和政策制定者提供了信息。

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Diseases. 2016 Feb 6;4(1):9. doi: 10.3390/diseases4010009.
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Factors Associated with Self-Injurious Behaviors in Children with Autism Spectrum Disorder: Findings from Two Large National Samples.自闭症谱系障碍儿童自我伤害行为的相关因素：来自两个大型全国样本的研究结果
J Autism Dev Disord. 2017 Feb;47(2):285-296. doi: 10.1007/s10803-016-2951-x.
3
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Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development.孕期母亲职业性接触哮喘诱发物与探索早期发育研究中的自闭症谱系障碍
J Autism Dev Disord. 2016 Nov;46(11):3458-3468. doi: 10.1007/s10803-016-2882-6.
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A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder.自闭症谱系障碍和注意力缺陷多动障碍执行功能缺陷的综述。
Neuropsychiatr Dis Treat. 2016 May 12;12:1191-202. doi: 10.2147/NDT.S104620. eCollection 2016.
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