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Flip the switch: BTG2-PRMT1 protein complexes antagonize pre-B-cell proliferation to promote B-cell development.

作者信息

Wu Glendon S, Bassing Craig H

机构信息

Immunology Graduate Group, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, 19104, PA, USA.

Divsion of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, 19104, PA, USA.

出版信息

Cell Mol Immunol. 2018 Sep;15(9):808-811. doi: 10.1038/cmi.2017.156. Epub 2018 Feb 12.

DOI:10.1038/cmi.2017.156
PMID:29429994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6203761/
Abstract
摘要

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本文引用的文献

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Nat Immunol. 2017 Aug;18(8):911-920. doi: 10.1038/ni.3774. Epub 2017 Jun 19.
2
Lymphocyte lineage-specific and developmental stage specific mechanisms suppress cyclin D3 expression in response to DNA double strand breaks.淋巴细胞谱系特异性和发育阶段特异性机制可抑制细胞周期蛋白D3的表达，以应对DNA双链断裂。
Cell Cycle. 2016 Nov;15(21):2882-2894. doi: 10.1080/15384101.2016.1198861. Epub 2016 Jun 21.
3
Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development.肿瘤抑制因子BTG1和BTG2调节小鼠早期B细胞发育。
Haematologica. 2016 Jul;101(7):e272-6. doi: 10.3324/haematol.2015.139675. Epub 2016 Apr 1.
4
BTG2: a rising star of tumor suppressors (review).BTG2：肿瘤抑制因子中的一颗后起之秀（综述）
Int J Oncol. 2015 Feb;46(2):459-64. doi: 10.3892/ijo.2014.2765. Epub 2014 Nov 18.
5
Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression.亚核周期蛋白 D3 隔室与增殖和免疫球蛋白可变基因抑制的协调调控。
J Exp Med. 2012 Nov 19;209(12):2199-213. doi: 10.1084/jem.20120800. Epub 2012 Oct 29.
6
Requirement for cyclin D3 in germinal center formation and function.cyclin D3 在生发中心形成和功能中的需求。
Cell Res. 2010 Jun;20(6):631-46. doi: 10.1038/cr.2010.55. Epub 2010 Apr 20.
7
The mammalian anti-proliferative BTG/Tob protein family.哺乳动物抗增殖BTG/Tob蛋白家族。
J Cell Physiol. 2010 Jan;222(1):66-72. doi: 10.1002/jcp.21919.
8
Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement.Btg1和Btg2在膜免疫球蛋白结合后通过精氨酸甲基化作用于WEHI-231细胞生长停滞中的作用。
Exp Cell Res. 2007 Jul 1;313(11):2356-66. doi: 10.1016/j.yexcr.2007.03.021. Epub 2007 Mar 30.
9
A unique function for cyclin D3 in early B cell development.细胞周期蛋白D3在早期B细胞发育中的独特功能。
Nat Immunol. 2006 May;7(5):489-97. doi: 10.1038/ni1324. Epub 2006 Apr 2.
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