Kudaĭberdiev Z M
Ter Arkh. 1986;58(5):56-60.
It was shown that the high-altitude conditions of the Pamirs and Tien Shan (2800-3600 m above the sea-level) modified the clinicofunctional signs and a course of the cor pulmonale (CP) in chronic bronchitis. CP was detected in the examined patients with chronic bronchitis. As compared to the conditions of foothills (760 m) CP in mountain-dwellers was more noticeable in terms of the signs of pulmonary arterial hypertension, right ventricular hypertrophy developed in them 5 years earlier. The first obvious signs of cardiac decompensation developed in the presence of moderate (noticeable at the foothills) right ventricular hypertrophy and were often (51.5% of the patients against 21.6% under the foothills conditions) accompanied by disturbance of cardiac rhythm and conduction.
结果表明，帕米尔高原和天山地区的高海拔条件（海拔2800 - 3600米）改变了慢性支气管炎患者的临床功能体征及肺心病（CP）的病程。在所检查的慢性支气管炎患者中检测到了肺心病。与山麓地区（海拔760米）的情况相比，山区居民的肺心病在肺动脉高压体征方面更为明显，右心室肥厚比山麓地区居民提前5年出现。心脏失代偿的最初明显体征出现在有中度（在山麓地区明显）右心室肥厚的情况下，并且常常（51.5%的患者，而山麓地区条件下为21.6%）伴有心律失常和传导障碍。
