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[红斑狼疮中的性激素]

[Sex hormones in lupus erythematosus].

作者信息

Vennemann F, Tholen S

出版信息

Z Hautkr. 1986 Jun 1;61(11):791-9.

PMID:2943085
Abstract

In 23 male and female patients suffering from systemic lupus erythematosus (LEV) and discoid (LEI), estradiol and androgen serum levels were determined. 11 female patients showed normal levels of estrogen. 4 out of 6 patients with LEV and 1 patient with LEI showed reduced levels of testosterone. 4 out of 5 men with LEV and 4 out of 7 men with LEI showed elevated levels of estradiol. 10 out of 12 patients showed reduced levels of testosterone. These results suggest that sexual hormones may play a part in the origination and course of LEV and LEI.

摘要

对23例患有系统性红斑狼疮(LEV)和盘状红斑狼疮(LEI)的男性和女性患者测定了血清雌二醇和雄激素水平。11例女性患者雌激素水平正常。6例LEV患者中有4例以及1例LEI患者睾酮水平降低。5例患有LEV的男性中有4例以及7例患有LEI的男性中有4例雌二醇水平升高。12例患者中有10例睾酮水平降低。这些结果表明性激素可能在LEV和LEI的发病及病程中起作用。

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