Suenaga I, Yamazaki T
Zentralbl Bakteriol Mikrobiol Hyg A. 1986 May;261(3):322-9. doi: 10.1016/s0176-6724(86)80049-9.
Ta:CF#1 mice lost their high susceptibility to Treponema hyodysenteriae infection after being mingled with Slc:ICR mice which had no susceptibility to the infection. Ta:CF#1 mice also lost susceptibility to the infection after being treated orally with fecal suspensions from Slc:ICR mice; treatment with heated (70 degrees C, 15 min) or filtered (pore size 0.2 micron) fecal suspensions did not cause a loss of susceptibility. Furthermore, even after the infection had established, Ta:CF#1 mice became free from T. hyodysenteriae and cecal lesions by oral treatment with the fecal suspensions. When Slc:ICR mice were treated with spectinomycin throughout the experiment, they became susceptible to the infection. These studies indicate that there exist eliminating organisms against T. hyodysenteriae in the gut of mice.
Ta:CF#1小鼠与对猪痢疾短螺旋体感染无易感性的Slc:ICR小鼠混养后，失去了对猪痢疾短螺旋体感染的高度易感性。Ta:CF#1小鼠经口服Slc:ICR小鼠的粪便悬液处理后，也失去了对该感染的易感性；用加热（70摄氏度，15分钟）或过滤（孔径0.2微米）的粪便悬液处理不会导致易感性丧失。此外，即使感染已经确立，Ta:CF#1小鼠经口服粪便悬液处理后，猪痢疾短螺旋体和盲肠病变也会消失。在整个实验过程中用壮观霉素处理Slc:ICR小鼠后，它们变得易受感染。这些研究表明，小鼠肠道中存在针对猪痢疾短螺旋体的清除性微生物。
