Siba P M, Pethick D W, Hampson D J
School of Veterinary Studies, Murdoch University, Australia.
Epidemiol Infect. 1996 Apr;116(2):207-16. doi: 10.1017/s0950268800052456.
Weaner pigs (n = 72) were fed 1 of 4 diets. These were based on either cooked rice and animal protein, cooked rice and lupin, wheat and lupin, or wheat and animal protein. Twenty-six of the pigs were slaughtered after 1 month. Those fed the highly digestible cooked rice and animal protein diet had drier colonic contents and faeces, lighter large intestines, and the contents of their large intestines had increased pH values and decreased total VFA concentrations. The other 46 were orally challenged with broth cultures of Serpulina hyodysenteriae, and were monitored for faecal excretion of the spirochaetes, and for the development of swine dysentery (SD). None of 18 pigs fed the cooked rice and animal protein diet developed colonic changes or disease, whereas most pigs on the other diets developed mucohaemorrhagic colitis and dysentery. The reduced fermentation that occurred in the large intestines of pigs fed cooked rice and animal protein was associated with a subsequent failure of colonization by S. hyodysenteriae, and resultant protection against SD.
断奶仔猪（n = 72）被喂食4种日粮中的1种。这些日粮分别基于熟米饭和动物蛋白、熟米饭和羽扇豆、小麦和羽扇豆，或小麦和动物蛋白。1个月后，26头猪被屠宰。那些喂食高消化率熟米饭和动物蛋白日粮的猪，其结肠内容物和粪便更干燥，大肠更轻，并且其大肠内容物的pH值升高，总挥发性脂肪酸浓度降低。另外46头猪经口服猪痢疾蛇形螺旋体肉汤培养物进行攻毒，并监测螺旋体的粪便排泄情况以及猪痢疾（SD）的发病情况。18头喂食熟米饭和动物蛋白日粮的猪均未出现结肠变化或疾病，而其他日粮组的大多数猪都出现了黏液出血性结肠炎和痢疾。喂食熟米饭和动物蛋白的猪大肠中发生的发酵减少，这与随后猪痢疾蛇形螺旋体的定植失败有关，并由此预防了猪痢疾。
