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高安动脉炎合并硬化性骨髓炎。

Takayasu Arteritis Coexisting with Sclerosing Osteomyelitis.

作者信息

Shirai Tsuyoshi, Hanaoka Riiza, Goto Yusuke, Kojima Ikuho, Ishii Yusho, Hoshi Yousuke, Fujita Yoko, Shirota Yuko, Fujii Hiroshi, Ishii Tomonori, Harigae Hideo

机构信息

Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Japan.

Department of Oral Diagnosis, Tohoku University Graduate School of Dentistry, Japan.

出版信息

Intern Med. 2018 Jul 1;57(13):1929-1934. doi: 10.2169/internalmedicine.0329-17. Epub 2018 Feb 9.

DOI:10.2169/internalmedicine.0329-17
PMID:29434141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6064701/
Abstract

We report a rare case of a 27-year-old woman with Takayasu arteritis (TAK) complicated by diffuse sclerosing osteomyelitis. She first presented with sclerosing osteomyelitis of the right mandible without evidence of arteritis in the carotid arteries. Eight months later, she complained of left neck pain, and imaging studies revealed the presence of arteritis in the left carotid artery. She was diagnosed with TAK, and immunosuppressive treatment was initiated, which was effective for both the arteritis and the osteomyelitis. Osteomyelitis is an important complication of TAK and bone scintigraphy is useful for its detection.

摘要

我们报告了一例罕见病例,一名27岁女性患有高安动脉炎(TAK)并伴有弥漫性硬化性骨髓炎。她最初表现为右下颌骨硬化性骨髓炎,颈动脉无动脉炎迹象。八个月后,她主诉左颈部疼痛,影像学检查显示左颈动脉存在动脉炎。她被诊断为TAK,并开始进行免疫抑制治疗,该治疗对动脉炎和骨髓炎均有效。骨髓炎是TAK的重要并发症,骨闪烁显像对其检测很有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/3dc8d42e1843/1349-7235-57-1929-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/0e32baec9292/1349-7235-57-1929-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/0264823208b5/1349-7235-57-1929-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/92cd71c376ba/1349-7235-57-1929-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/3dc8d42e1843/1349-7235-57-1929-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/0e32baec9292/1349-7235-57-1929-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/0264823208b5/1349-7235-57-1929-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/92cd71c376ba/1349-7235-57-1929-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6064701/3dc8d42e1843/1349-7235-57-1929-g004.jpg

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Rev Assoc Med Bras (1992). 2017 Apr;63(4):303-306. doi: 10.1590/1806-9282.63.04.303.
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J Rheumatol. 2017 Jan;44(1):127-128. doi: 10.3899/jrheum.160491.
3
Ibandronate treatment of diffuse sclerosing osteomyelitis of the mandible: Pain relief and insight into pathogenesis.
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Front Immunol. 2025 Jan 7;15:1473100. doi: 10.3389/fimmu.2024.1473100. eCollection 2024.
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