Dagan O, Barak Y, Metzker A
Division of Pediatric Dermatology, Children's Medical Center of Israel, Petah Tiqva.
Pediatr Dermatol. 1995 Mar;12(1):39-42. doi: 10.1111/j.1525-1470.1995.tb00122.x.
A 9-month-old infant had pyoderma gangrenosum (PG) and sterile osteomyelitis. Three years later the patient developed Takayasu arteritis (TA). Sterile osteomyelitis was reported in approximately 30 patients with different skin lesions, but never together with pyoderma gangrenosum. The association of PG and TA has been reported rarely, and then mainly in adults or in children over age 9 years. This rare association should alert physicians with a case of infantile PG of unknown etiology to consider the possible diagnosis of TA.
一名9个月大的婴儿患有坏疽性脓皮病（PG）和无菌性骨髓炎。三年后，该患者患上了大动脉炎（TA）。约30例患有不同皮肤病变的患者报告了无菌性骨髓炎，但从未与坏疽性脓皮病同时出现。PG与TA的关联鲜有报道，且主要见于成人或9岁以上儿童。这种罕见的关联应提醒医生，对于病因不明的婴儿PG病例，要考虑TA的可能诊断。
