Merchán Nelson, Yeung Caleb M, Garcia Jayden, Schwab Joseph H, Raskin Kevin A, Newman Erik T, Lozano-Calderón Santiago A
Department of Orthopaedic Oncology Harvard Medical School, Massachusetts General Hospital Boston MA, USA.
Arch Bone Jt Surg. 2022 Feb;10(2):190-203. doi: 10.22038/abjs.2021.53494.2655.
Patellar tumors are rare but certainly must be considered in the differential diagnosis in patients with knee pain. Diagnosis can be challenging as often patellar neoplasms are confused with benign conditions and their clinical presentation is usually not specific. We performed an institutional and a literature review to determine what are the most common tumors affecting the patella and what is the best management.
This is a case series from our institution including all patients with benign, malignant, and metastatic patellar neoplasms. Charts were reviewed for patient demographics, clinical presentation, pathology characteristics, radiographic classification, and oncologic and functional outcomes.
Twenty-four patients were identified; twelve patients had benign lesions, 10 metastatic and 2 primary malignant tumors. Chondroblastoma and Giant Cell Tumor were the most common tumors. Management of benign lesions with intralesional curettage and packing with bone graft or cement demonstrated excellent results with no local recurrence. In terms of malignant tumors, the spectrum of treatment is variable; it could range from medical management alone or in combination with surgical procedures to total patellectomy with reconstruction of the extensor mechanism.
Patellar tumors should be part of the differential in patients with chronic knee pain that does not respond to initial conservative interventions. Recurrence rate with intralesional curettage and bone grafting or cement packing is very low and therefore should be the treatment of choice for benign intraosseous neoplasms. Resection with negative margins in malignant neoplasms or bone metastasis decreases local recurrence but only in the former group there is a potential impact in survival.
髌骨肿瘤较为罕见,但在膝关节疼痛患者的鉴别诊断中肯定需要考虑。诊断可能具有挑战性,因为髌骨肿瘤常与良性疾病相混淆,且其临床表现通常不具特异性。我们进行了一项机构研究和文献综述,以确定影响髌骨的最常见肿瘤以及最佳治疗方法。
这是来自我们机构的一个病例系列,包括所有患有良性、恶性和转移性髌骨肿瘤的患者。对病历进行了回顾,以了解患者的人口统计学特征、临床表现、病理特征、影像学分类以及肿瘤学和功能结局。
共确定了24例患者;12例为良性病变,10例为转移性肿瘤,2例为原发性恶性肿瘤。软骨母细胞瘤和骨巨细胞瘤是最常见的肿瘤。采用病灶内刮除并填充骨移植材料或骨水泥治疗良性病变,效果良好,无局部复发。对于恶性肿瘤,治疗方案各不相同;范围可从单纯药物治疗或药物与手术联合治疗到全髌骨切除术并重建伸膝装置。
髌骨肿瘤应作为慢性膝关节疼痛且对初始保守治疗无反应患者鉴别诊断的一部分。病灶内刮除并植骨或骨水泥填充的复发率非常低,因此应作为良性骨内肿瘤的首选治疗方法。恶性肿瘤或骨转移瘤切除边缘阴性可降低局部复发率,但只有前一组对生存率有潜在影响。