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[髋臼周围截骨术——年龄对与患者相关的结果有何影响?:一项为期5年的前瞻性研究]

[Periacetabular osteotomy-what influence does age have on patient-relevant results? : A prospective 5‑year investigation].

作者信息

Franken L, Thielemann F, Postler A, Blum S, Hartmann A, Günther K-P, Goronzy J

机构信息

UniversitätsCentrum für Orthopädie & Unfallchirurgie am Universitätsklinikum Carl Gustav Carus Dresden, Medizinische Fakultät, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

Institut und Poliklinik für Radiologische Diagnostik am Universitätsklinikum Carl Gustav Carus Dresden, Medizinische Fakultät, Technische Universität Dresden, Dresden, Deutschland.

出版信息

Orthopade. 2018 Mar;47(3):228-237. doi: 10.1007/s00132-017-3523-2.

Abstract

INTRODUCTION

Periacetabular osteotomy (PAO) is an effective procedure in treatment of symptomatic hip dysplasia. To achieve a good outcome a strict patient selection has to be applied. The aim of this study was to evaluate the influence of patient age at surgery on clinical outcome.

METHODS

In a prospective study 86 patients (106 hips) underwent clinical and radiographic follow-up at a mean time of 5 years (2.5-8.5 years) after PAO. Patient-related outcome measurements (PROMs: EQ-5D, WOMAC, OHS, GTO) were applied preoperatively as well as postoperatively and the deformity correction as well as development of osteoarthritis were evaluated. In order to analyze the influence of patient age at surgery on clinical outcome, we subdivided the patient cohort into four different age groups (<20 years, 20-29 years, 30-39 years, >40 years).

RESULTS

Of the patients 90% were very satisfied or satisfied with the results 5 years after surgery, and in all age groups PROMs significantly increased. Even though preoperative as well as postoperative algofunction declined in cohorts with increasing age, the overall benefit as measured in WOMAC and EQ-5D scores was equal in all age groups. Increasing age is associated with a progression in osteoarthritis as well as a higher conversion rate to total arthroplasty.

DISCUSSION

Age is an important influencing factor on the long-term outcome after PAO. A certain age as cut off for indications could not be identified in this study. Even patients in the age groups 30-39 years and > 40 years showed PROM improvement and satisfaction with outcome at medium-term follow-up. The expected success rate has to be discussed preoperatively with the patient; however, as a higher conversion rate to hip arthroplasty as well as progressive osteoarthritis is associated with higher age, not only patient age alone but also morphological characteristics of the hip joint have to be taken into consideration.

摘要

引言

髋臼周围截骨术(PAO)是治疗有症状的髋关节发育不良的一种有效手术。为了取得良好的效果,必须严格选择患者。本研究的目的是评估手术时患者年龄对临床结果的影响。

方法

在一项前瞻性研究中,86例患者(106髋)在PAO术后平均5年(2.5 - 8.5年)接受了临床和影像学随访。术前及术后均采用与患者相关的结局测量指标(PROMs:EQ - 5D、WOMAC、OHS、GTO),并评估畸形矫正情况以及骨关节炎的发展。为了分析手术时患者年龄对临床结果的影响,我们将患者队列分为四个不同年龄组(<20岁、20 - 29岁、30 - 39岁、>40岁)。

结果

90%的患者对术后5年的结果非常满意或满意,且所有年龄组的PROMs均显著提高。尽管随着年龄增长,术前及术后的疼痛功能均有所下降,但所有年龄组中以WOMAC和EQ - 5D评分衡量的总体获益是相同的。年龄增长与骨关节炎的进展以及全关节置换术的更高转换率相关。

讨论

年龄是PAO术后长期结局的一个重要影响因素。本研究未能确定一个作为适应证界限的特定年龄。即使是30 - 39岁和>40岁年龄组的患者在中期随访时也显示出PROMs改善及对结局的满意。术前必须与患者讨论预期的成功率;然而,由于全髋关节置换术的更高转换率以及进行性骨关节炎与更高年龄相关,不仅要考虑患者年龄,还必须考虑髋关节的形态特征。

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