Hum Nutr Clin Nutr. 1986 Jul;40(4):249-54.
Forty-eight children, aged 2-5 years, presenting with watery diarrhoea of less than 48 h duration at home prior to hospitalization, were admitted into a randomized controlled clinical trial, 24 children being treated during the first 24 h of admission with oral rehydration solution (ORS) alone and 24 children being given 'ORS plus boiled-rice feeding'. The latter group received boiled-rice to supply at least 55 kcal/kg/d (about 150 g boiled-rice per feed, given four times daily). Vibrio cholerae were isolated by stool culture on admission from all children. No antibiotics were given. Clinical characteristics of children in the two treatment groups were comparable. Among children given 'ORS plus boiled rice', there was a significant increase in volume of diarrhoea stools (P less than 0.05), duration of diarrhoea in hospital (P less than 0.01), and more frequent diarrhoea motions (not significant statistically). However, the children fed boiled rice absorbed and retained 176 ml more fluid, and had gain in body weight comparable to that observed in children who were not fed during the first 24 h of hospitalization.
48名2至5岁的儿童，在住院前在家中出现持续时间少于48小时的水样腹泻，被纳入一项随机对照临床试验。24名儿童在入院后的头24小时仅接受口服补液盐（ORS）治疗，另外24名儿童接受“ORS加喂米汤”治疗。后一组接受米汤，以提供至少55千卡/千克/天（每次喂食约150克米汤，每天喂4次）。所有儿童入院时粪便培养均分离出霍乱弧菌。未给予抗生素。两个治疗组儿童的临床特征具有可比性。在给予“ORS加米汤”的儿童中，腹泻粪便量显著增加（P<0.05），住院腹泻持续时间显著增加（P<0.01），腹泻次数更频繁（统计学上无显著差异）。然而，喂米汤的儿童多吸收并保留了176毫升液体，体重增加与住院头24小时未喂食的儿童相当。
