迈向高质量、实用的儿童和青少年精神障碍实践指南：系统评价与共识达成的方案

Towards high-quality, useful practice guidelines for child and youth mental health disorders: protocol for a systematic review and consensus exercise.

作者信息

Bennett Kathryn, Duda Stephanie, Brouwers Melissa, Szatmari Peter, Newton Amanda, McLennan John, Sundar Purnima, Cleverley Kristin, Charach Alice, Henderson Joanna, Courtney Darren, Rice Maureen

机构信息

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

Department of Oncology, McMaster University, Hamilton, Ontario, Canada.

出版信息

BMJ Open. 2018 Feb 6;8(2):e018053. doi: 10.1136/bmjopen-2017-018053.

DOI:10.1136/bmjopen-2017-018053

PMID:29437752

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5829788/

Abstract

INTRODUCTION

The quality of clinical practice guidelines (PGs) has not been evaluated in child and youth mental health (CYMH). To address this gap, we will: (1) conduct a systematic review (SR) to answer the question 'among eligible PGs relevant to the prevention or treatment of CYMH conditions, which PGs meet criteria for minimum and high quality?'; (2) apply nominal group methods to create recommendations for how CYMH PG quality, completeness and usefulness can be strengthened.

METHODS AND ANALYSIS

SR: Potentially eligible PGs will be identified in 12 databases using a reproducible search strategy developed by a research librarian. Trained raters will: (1) apply prespecified criteria to identify eligible PGs relevant to depression, anxiety, suicidality, bipolar disorder, behaviour disorder (attention-deficit hyperactivity disorder, oppositional defiant disorder, conduct disorder) and substance use disorder; (2) extract descriptive data and (3) assess PG quality using the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool. Scores on three AGREE II domains (rigour of development, stakeholder involvement, editorial independence) will designate PGs as minimum (≥50%) or high quality (≥70%). Nominal group: Four CYMH PG knowledge user groups (clinicians, mental health service planners, youth and adult family members) will participate in structured exercises derived using nominal group methods to generate recommendations to improve PG quality, completeness and usefulness.

ETHICS AND DISSEMINATION

Ethics approval is not required. Study products will be disseminated as follows. A cross-platform website will house eligible CYMH PGs and their quality ratings. Twitter and Facebook tools will promote it to a wide variety of PG users. Data from Google Analytics, Twitonomy and Altmetrics will inform usage evaluation. Complementary educational workshops will be conducted for CYMH professionals. Print materials and journal articles will be produced.

PROSPERO REGISTRATION NUMBER

CRD42017060738.

摘要

引言

儿童和青少年心理健康（CYMH）领域的临床实践指南（PGs）质量尚未得到评估。为填补这一空白，我们将：（1）进行一项系统评价（SR），以回答“在与CYMH疾病预防或治疗相关的合格PGs中，哪些PGs符合最低质量和高质量标准？”这一问题；（2）应用名义群体法，就如何加强CYMH PG的质量、完整性和实用性提出建议。

方法与分析

系统评价：将使用由研究馆员制定的可重复搜索策略，在12个数据库中识别潜在合格的PGs。经过培训的评估人员将：（1）应用预先设定的标准，识别与抑郁症、焦虑症、自杀倾向、双相情感障碍、行为障碍（注意力缺陷多动障碍、对立违抗障碍、品行障碍）和物质使用障碍相关的合格PGs；（2）提取描述性数据；（3）使用《研究与评价指南评估》（AGREE II）工具评估PG质量。AGREE II三个领域（制定的严谨性、利益相关者参与度、编辑独立性）的得分将把PGs指定为最低质量（≥50%）或高质量（≥70%）。名义群体：四个CYMH PG知识用户群体（临床医生、心理健康服务规划者、青少年和成年家庭成员）将参与使用名义群体法得出的结构化练习，以生成改进PG质量、完整性和实用性的建议。