Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Adv Nutr. 2018 Jan 1;9(1):51-57. doi: 10.1093/advances/nmx014.
Dietary supplements can have beneficial effects on a number of risk factors for cardiovascular diseases, and interest in the use of nonpharmacologic nutraceutical-based treatments for cardiovascular disorders is growing. The aim of this review is to present the role of dietary supplements with antiplatelet activity in the prophylaxis and treatment of cardiovascular disorders. In addition, this paper describes their effects on another very important element of hemostasis-blood coagulation. However, because controlled human clinical experiments are too limited to clearly identify the antiplatelet and anticoagulant properties of dietary supplements, used alone or in combination with classical antiplatelet therapy (e.g., with aspirin), most information in this article is based on in vitro studies. Therefore, it cannot be unequivocally stated whether dietary supplements are universally safe and bring benefits to all. Some authors suggest that blood platelet count and function should be monitored in patients taking such supplements, especially before and after surgery, as well as other hemostasis parameters such as coagulation times.
膳食补充剂对心血管疾病的许多危险因素都有有益影响，人们对使用非药物营养治疗心血管疾病的兴趣日益增加。本综述的目的是介绍具有抗血小板活性的膳食补充剂在预防和治疗心血管疾病中的作用。此外，本文还描述了它们对另一个非常重要的止血元素-凝血的影响。然而，由于对照人体临床试验过于有限，无法清楚地确定膳食补充剂的抗血小板和抗凝特性，无论是单独使用还是与经典抗血小板治疗（例如与阿司匹林联合使用），本文中的大多数信息都基于体外研究。因此，不能明确地说膳食补充剂是否普遍安全并对所有人都有益。一些作者建议，服用此类补充剂的患者应监测血小板计数和功能，尤其是在手术前后，以及其他止血参数，如凝血时间。
