MOG 抗体脱髓鞘疾病：产后严重脑桥脑炎和横贯性脊髓炎一例。
MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis.
机构信息
Neurology Department, Università del Piemonte Orientale, Azienda Ospedaliera-Universitaria Maggiore della Carità, Novara, Italy.
Neurology Department, Università del Piemonte Orientale, Azienda Ospedaliera-Universitaria Maggiore della Carità, Novara, Italy.
出版信息
Mult Scler Relat Disord. 2018 Apr;21:9-10. doi: 10.1016/j.msard.2018.02.006. Epub 2018 Feb 8.
INTRODUCTION
Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement.
CASE REPORT
A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression.
CONCLUSION
MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.
简介
少突胶质细胞髓鞘糖蛋白抗体（MOG-IgG）相关疾病具有广泛的临床表现，包括脑干受累。
病例报告
一位产后突发严重脑桥炎导致呼吸衰竭的患者（12 年前曾患有轻度横贯性脊髓炎）。尽管病情进展迅速，但在接受血浆置换治疗后，她恢复良好，且在免疫抑制治疗后无进一步复发。
结论
MOG-IgG 疾病在发病后数年可能复发并累及脑干。经治疗后，预后良好。
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