Department of Health Outcomes and Biomedical Informatics, University of Florida, P.O. Box 100177, Gainesville, FL, 32610, USA.
Health Qual Life Outcomes. 2018 Feb 13;16(1):34. doi: 10.1186/s12955-018-0858-2.
Although Short Form (SF)-12 × 2® has been extensively studied and used as a valid measure of health-related quality of life in a variety of population groups, no systematic studies have described the reliability of the measure in patients with behavioral conditions or serious mental illness (SMI).
We assessed the internal consistency, split-half reliability and annual test-retest correlations in a sample of 1587 participants with either a combination of physical and behavioral conditions or SMI. The Mosier's alpha was 0.70 for the Physical Composite Scale (PCS) and 0.69 for the Mental Health Composite Scale (MCS), indicating good internal consistency. We observed strong correlations between physical functioning, physical role and body pain scales (r = 0.55-0.56), and between social functioning, emotional role, and mental health (r = 0.53-0.58). We calculated split-half reliabilities to be 0.74 for physical functioning, 0.75 for physical role, 0.73 for emotional role and 0.65 for mental health respectively. We assessed the annual test-retest correlation using intraclass correlation (ICC) and found an ICC of 0.61 for PCS and 0.57 for MCS composite scores, adjusting for age, sex, race/ethnicity, and CRG. We found no decline in the correlations between baseline and the following study years until year 3.
Our results encourage using SF-12v2® to assess health-related quality of life in the Medicaid population with combined physical and behavioral conditions or similar cohorts.
The WIN study was registered with clinicaltrials.gov on April 22, 2015.
NCT02440906 . Retrospectively registered.
尽管简短表格（SF）-12×2®已在各种人群中作为健康相关生活质量的有效测量方法得到广泛研究和应用，但尚无系统研究描述该测量方法在行为障碍或严重精神疾病（SMI）患者中的可靠性。
我们评估了 1587 名既有躯体疾病又有行为障碍或 SMI 的患者样本中的内部一致性、半分信度和年度测试-重测相关性。物理综合量表（PCS）的 Mosier's 阿尔法值为 0.70，心理健康综合量表（MCS）的 Mosier's 阿尔法值为 0.69，表明具有良好的内部一致性。我们观察到生理功能、生理角色和身体疼痛量表之间存在很强的相关性（r=0.55-0.56），以及社会功能、情感角色和心理健康之间的相关性（r=0.53-0.58）。我们计算半分信度分别为 0.74 分（生理功能）、0.75 分（生理角色）、0.73 分（情感角色）和 0.65 分（心理健康）。我们使用组内相关系数（ICC）评估年度测试-重测相关性，发现 PCS 的 ICC 为 0.61，MCS 综合评分的 ICC 为 0.57，调整了年龄、性别、种族/民族和 CRG。我们发现直到第 3 年，基线与后续研究年之间的相关性没有下降。
我们的研究结果鼓励在同时患有躯体和行为障碍或类似队列的 Medicaid 人群中使用 SF-12v2®评估健康相关生活质量。
WIN 研究于 2015 年 4 月 22 日在 clinicaltrials.gov 上注册。
NCT02440906。回顾性注册。
