Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Curr Pain Headache Rep. 2019 May 30;23(7):47. doi: 10.1007/s11916-019-0786-9.
Cerebral venous thrombosis (CVT) is a neurovascular disease caused by a thrombotic occlusion of either a dural sinus or cerebral vein. CVT results in a variety of neurological symptoms with the most common being headache. The purpose of this review is to characterize CVT, describe the headache pattern, and, finally, provide an update to date review of diagnostic and treatment options for this condition.
CVT is a very difficult disease to diagnose due to the variability in both patient presentation and imaging findings. Recent literature has attempted to standardize its risk factors, diagnosis, and treatment modalities. Additionally, new laboratory studies are being investigated for CVT patients who present with isolated headaches. CVT is a debilitating disease requiring immediate medical or surgical intervention. Because the disease can mask as a multitude of neurological deficits, patients are not properly diagnosed. Headache is the most common patient presentation. The quality of this headache is highly variable with no specific location or pattern. New literature has provided insight into potential diagnostic and treatment options for CVT patients. However, further large-scale cohort studies are necessary to standardize the care for this disease.
脑静脉血栓形成(CVT)是一种由硬脑膜窦或脑静脉血栓形成引起的血管疾病。CVT 导致多种神经症状,最常见的是头痛。本综述的目的是描述 CVT 的特征,描述头痛模式,并对该病的诊断和治疗选择进行最新的综述。
由于患者表现和影像学发现的多样性,CVT 的诊断非常困难。最近的文献试图使该病的危险因素、诊断和治疗方式标准化。此外,还对仅表现为头痛的 CVT 患者进行了新的实验室研究。CVT 是一种使人虚弱的疾病,需要立即进行医疗或手术干预。由于该疾病可能掩盖多种神经功能缺损,因此患者未得到正确诊断。头痛是最常见的患者表现。这种头痛的质量变化很大,没有特定的位置或模式。新的文献提供了对 CVT 患者潜在诊断和治疗选择的深入了解。然而,需要进一步的大规模队列研究来规范该病的治疗。