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口腔反应性增生性病变:一项回顾性调查研究及文献综述

Reactive hyperplastic lesions of the oral cavity: A retrospective survey study and literature review.

作者信息

Sangle Varsha Ajit, Pooja V K, Holani Anuja, Shah Nishat, Chaudhary Mayur, Khanapure Sneha

机构信息

Department of Oral Pathology and Microbiology, MIDSR Dental College, Latur, India.

Department of Oral Pathology and Microbiology, BVU Dental College and Hospital, Pune, Maharashtra, India.

出版信息

Indian J Dent Res. 2018 Jan-Feb;29(1):61-66. doi: 10.4103/ijdr.IJDR_599_16.

Abstract

CONTEXT

The reactive lesions are relatively common in the oral cavity because of the frequency with which the tissues are injured. They often result from a known stimulus or injury such as dental plaque, calculus, or foreign material.

AIMS

: The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at MIDSR, Dental College and Hospital, Latur, Maharashtra, and to compare these data with those of previously reported studies.

SETTINGS AND DESIGN

The patient case files from the Department of Oral and Maxillofacial Pathology from June 2010 to May 2016 were reviewed for cases of RHLs of the oral cavity.

SUBJECTS AND METHODS

Both clinical and histopathological diagnosis of reactive lesions was selected for the study. Data including the type of the lesion, age, gender, and the site involved were collected.

STATISTICAL ANALYSIS USED

Descriptive statistics was applied to the data and differences in frequencies among groups were evaluated using SPSS (IBM Corporation) software.

RESULTS

: A total of 155 histologically diagnosed cases of RHLs were obtained with a prevalence of 11.7%. The data consist of 56 (36.1%) males and 99 (63.9%) females. The most common lesion clinically was traumatic fibroma (36.5%) and histologically fibrous hyperplasia (37.4%). The reactive lesions clinically presented as either sessile (51%) or pedunculated (49%) lesions.

CONCLUSIONS

The clinical features of reactive hyperplasia among our patients were similar to those reported previously with divergence in some analyzed data. The novelty in our study was the correlation between histopathology and clinical features which were not reported in literature till date.

摘要

背景

由于口腔组织受伤的频率较高,反应性病变在口腔中相对常见。它们通常由已知的刺激或损伤引起,如牙菌斑、牙结石或异物。

目的

本研究的目的是回顾位于马哈拉施特拉邦拉图尔市的牙科学院和医院MIDSR口腔反应性增生性病变(RHLs)的临床病理特征,并将这些数据与先前报道的研究数据进行比较。

设置与设计

回顾了口腔颌面病理科2010年6月至2016年5月期间的患者病例档案,以查找口腔RHLs病例。

研究对象与方法

本研究选择了反应性病变的临床和组织病理学诊断。收集了包括病变类型、年龄、性别和受累部位在内的数据。

统计分析方法

对数据应用描述性统计,并使用SPSS(IBM公司)软件评估组间频率差异。

结果

共获得155例经组织学诊断的RHLs病例,患病率为11.7%。数据包括56例(36.1%)男性和99例(63.9%)女性。临床上最常见的病变是创伤性纤维瘤(36.5%),组织学上是纤维增生(37.4%)。反应性病变临床上表现为无蒂(51%)或有蒂(49%)病变。

结论

我们患者中反应性增生的临床特征与先前报道的相似,但在一些分析数据上存在差异。我们研究的新颖之处在于组织病理学与临床特征之间的相关性,这在迄今为止的文献中尚未报道。

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