Pytel Aleksandra, Demczyszak Iwona, Sutkowska Edyta, Rosińczuk Joanna, Kuberka Izabela, Kołtuniuk Aleksandra
Department of Medical Rehabilitation, Wroclaw Medical University, Poland.
Department of Nervous System, Wroclaw Medical University, Poland.
Adv Clin Exp Med. 2017 Dec;26(9):1411-1418. doi: 10.17219/acem/68900.
Rheumatoid arthritis (RA) is an incurable disease resulting in progressive disability, which is associated with the loss of productivity and the inability to earn money, which might lead to a financial burden on the patient's family. Undoubtedly, the clinical picture of the disease and its consequences lead to the reduction of the quality of life.
The aim of this study is to evaluate the influence of selected factors on the subjective assessment of the quality of life and general health of patients with RA.
The study was conducted among 270 patients with RA treated at the Department of Rheumatology and Internal Medicine. The quality of life and general health were assessed with the use of the SF-36 and the GHQ-30 questionnaires.
In the study group, a statistically significant correlation between the results of the SF-36 and the GHQ-30 questionnaires was observed. It has been shown that the level of role limitations due to physical health problems (RP) is mostly affected by interpersonal relationships based on GHQ-30 questionnaire (p = 0.002), general health (GHQ-30) (p = 0.001) and subjective health condition (SF-36) (p < 0.001). In contrast, general health (GHQ-30) is positively affected by education (p = 0.003) and professional activity (p = 0.001), and negatively affected by a positive family history of RA (p = 0.002), frequent hospitalization (p = 0.008) and poor subjective health condition (p < 0.001).
People with poor subjective health condition are characterized by more limited activity due to physical health and lower general health condition. General health (GHQ-30) in patients with rheumatoid arthritis is influenced by education, place of residence, professional work, family history of RA and subjective health status.
类风湿性关节炎（RA）是一种无法治愈的疾病，会导致进行性残疾，这与生产力丧失和无法挣钱相关，可能给患者家庭带来经济负担。毫无疑问，该疾病的临床表现及其后果会导致生活质量下降。
本研究旨在评估选定因素对类风湿性关节炎患者生活质量主观评估和总体健康状况的影响。
该研究在风湿病与内科治疗的270例类风湿性关节炎患者中进行。使用SF - 36和GHQ - 30问卷评估生活质量和总体健康状况。
在研究组中，观察到SF - 36和GHQ - 30问卷结果之间存在统计学显著相关性。结果表明，基于GHQ - 30问卷，身体健康问题导致的角色限制水平（RP）主要受人际关系（p = 0.002）、总体健康（GHQ - 30）（p = 0.001）和主观健康状况（SF - 36）（p < 0.001）影响。相比之下，总体健康（GHQ - 30）受教育程度（p = 0.003）和职业活动（p = 0.001）的正向影响，受类风湿性关节炎阳性家族史（p = 0.002）、频繁住院（p = 0.008）和主观健康状况不佳（p < 0.001）的负向影响。
主观健康状况不佳的人因身体健康导致的活动受限更多，总体健康状况更低。类风湿性关节炎患者的总体健康（GHQ - 30）受教育程度、居住地点、职业工作、类风湿性关节炎家族史和主观健康状况影响。
