Bekkelund S I, Husby G, Mellgren S I
Department of Neurology, University Hospital, Tromsø, Norway.
Clin Exp Rheumatol. 1995 Jul-Aug;13(4):471-5.
To study quality of life parameters in patients with rheumatoid arthritis and the possible association of these parameters with disease activity.
Fifty-two women with rheumatoid arthritis and 52 controls completed two self reporting psychiatric screening tests: the General Health Questionnaire (GHQ - 30) and the Cantril Ladder scale. The number of psychiatric cases detected was not significantly higher for either group using the GHQ score S+ as the criterion.
Comparing the GHQ scores, patients showed a higher score compared with the controls (p = 0.02). The patients scored significantly higher on feelings of incompetance (p = 0.004), but not on the other subgroups of psychiatric factors. The patients reported lower life satisfaction on the Cantril self anchoring ladder (p = 0.0001). The functional capacity score was positively associated with the GHQ score. No association was detected between disease duration or the other disease activity parameters and either the GHQ score or the life satisfaction score.
This inconsistant relationship between clinical parameters and quality of life scores may be due to the fact that RA patients suffer from a chronic disease, or it may reflect an impaired psychosocial status in the patients. This study demonstrates that the increased psychological disturbances in women with RA is mainly explained by feelings of incompetance.
研究类风湿性关节炎患者的生活质量参数以及这些参数与疾病活动的可能关联。
52名类风湿性关节炎女性患者和52名对照者完成了两项自我报告的精神筛查测试：一般健康问卷（GHQ - 30）和坎特里尔阶梯量表。以GHQ得分S+为标准，两组中检测出的精神病例数均无显著差异。
比较GHQ得分，患者得分高于对照者（p = 0.02）。患者在无能感方面得分显著更高（p = 0.004），但在精神因素的其他亚组中得分无差异。患者在坎特里尔自我定位阶梯上报告的生活满意度较低（p = 0.0001）。功能能力得分与GHQ得分呈正相关。未检测到疾病持续时间或其他疾病活动参数与GHQ得分或生活满意度得分之间存在关联。
临床参数与生活质量得分之间这种不一致的关系可能是由于类风湿性关节炎患者患有慢性疾病，或者可能反映了患者心理社会状态受损。本研究表明，类风湿性关节炎女性患者心理障碍增加主要是由无能感所致。
