Hale Amanda R, Ross Ann H
Department of Biological Sciences, North Carolina State University;
Department of Biological Sciences, North Carolina State University.
J Vis Exp. 2018 Jan 29(131):56713. doi: 10.3791/56713.
The purpose of this paper is to introduce a promising, novel method to aid in the assessment of bone quality in forensically relevant skeletal remains. BMD is an important component of bone's nutritional status and in skeletal remains of both juveniles and adults, and it can provide information about bone quality. For adults remains, it can provide information on pathological conditions or when bone insufficiency may have occurred. In juveniles, it provides a useful metric to elucidate cases of fatal starvation or neglect, which are generally difficult to identify. This paper provides a protocol for the anatomical orientation and analysis of skeletal remains for scanning via dual-energy X-ray absorptiometry (DXA). Three case studies are presented to illustrate when DXA scans can be informative to the forensic practitioner. The first case study presents an individual with observed longitudinal fractures in the weight bearing bones and DXA is used to assess bone insufficiency. BMD is found to be normal suggesting another etiology for the fracture pattern present. The second case study employed DXA to investigate suspected chronic malnutrition. The BMD results are consistent with results from long bone lengths and suggest the juvenile had suffered from chronic malnutrition. The final case study provides an example where fatal starvation in a fourteen-month infant is suspected, which supports autopsy findings of fatal starvation. DXA scans showed low bone mineral density for chronological age and is substantiated by traditional assessments of infant health. However, when dealing with skeletal remains taphonomic alterations should be considered before applying this method.
本文的目的是介绍一种有前景的新方法,以协助评估法医相关骨骼遗骸的骨质。骨密度是骨骼营养状况的重要组成部分,在青少年和成年人的骨骼遗骸中都能提供有关骨质的信息。对于成年人遗骸,它可以提供有关病理状况或骨质不足可能发生时间的信息。对于青少年,它提供了一个有用的指标来阐明致命饥饿或忽视的案例,这些案例通常难以识别。本文提供了一个通过双能X线吸收测定法(DXA)扫描骨骼遗骸的解剖定位和分析方案。给出了三个案例研究,以说明DXA扫描何时能为法医从业者提供有用信息。第一个案例研究展示了一名在承重骨中观察到纵向骨折的个体,通过DXA评估骨质不足。发现骨密度正常,表明存在其他导致骨折模式的病因。第二个案例研究使用DXA调查疑似慢性营养不良的情况。骨密度结果与长骨长度的结果一致,表明该青少年患有慢性营养不良。最后一个案例研究提供了一个疑似14个月大婴儿死于饥饿的例子,这支持了尸检关于致命饥饿的结果。DXA扫描显示按年龄计算的骨矿物质密度较低,并得到了对婴儿健康的传统评估的证实。然而,在应用此方法时,处理骨骼遗骸时应考虑埋藏学改变。