Lonie D S, Harper N J
Anaesthesia. 1986 Jul;41(7):703-7. doi: 10.1111/j.1365-2044.1986.tb12835.x.
Eighty-seven patients undergoing routine laparoscopy were divided randomly into two groups to study the effect of nitrous oxide anaesthesia on the incidence of postoperative vomiting. Patients in group A received nitrous oxide as part of their anaesthetic, while in group B nitrous oxide was omitted. Significantly fewer patients in group B vomited when compared with group A (17 percent and 49 percent respectively; p less than 0.005). We suggest that an anaesthetic technique which avoids nitrous oxide may be especially indicated in patients undergoing laparoscopy.
