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澳大利亚社区样本中基于网络的自杀念头自助项目的有效性:随机对照试验

Effectiveness of a Web-Based Self-Help Program for Suicidal Thinking in an Australian Community Sample: Randomized Controlled Trial.

作者信息

van Spijker Bregje Aj, Werner-Seidler Aliza, Batterham Philip J, Mackinnon Andrew, Calear Alison L, Gosling John A, Reynolds Julia, Kerkhof Ad Jfm, Solomon Daniela, Shand Fiona, Christensen Helen

机构信息

Centre for Mental Health Research, Australian National University, Canberra, Australia.

Black Dog Institute, Department of Medicine, University of New South Wales, Randwick, Australia.

出版信息

J Med Internet Res. 2018 Feb 14;20(2):e15. doi: 10.2196/jmir.8595.

Abstract

BACKGROUND

Treatment for suicidality can be delivered online, but evidence for its effectiveness is needed.

OBJECTIVE

The goal of our study was to examine the effectiveness of an online self-help intervention for suicidal thinking compared to an attention-matched control program.

METHODS

A 2-arm randomized controlled trial was conducted with assessment at postintervention, 6, and, 12 months. Through media and community advertizing, 418 suicidal adults were recruited to an online portal and were delivered the intervention program (Living with Deadly Thoughts) or a control program (Living Well). The primary outcome was severity of suicidal thinking, assessed using the Columbia Suicide Severity Rating Scale.

RESULTS

Intention-to-treat analyses showed significant reductions in the severity of suicidal thinking at postintervention, 6, and 12 months. However, no overall group differences were found.

CONCLUSIONS

Living with Deadly Thoughts was of no greater effectiveness than the control group. Further investigation into the conditions under which this program may be beneficial is now needed. Limitations of this trial include it being underpowered given the effect size ultimately observed, a high attrition rate, and the inability of determining suicide deaths or of verifying self-reported suicide attempts.

TRIAL REGISTRATION

Australian New Zealand Clinical Trials Registry ACTRN12613000410752; https://www.anzctr.org.au/ Trial/Registration/TrialReview.aspx?id=364016 (Archived by WebCite at http://www.webcitation.org/6vK5FvQXy); Universal Trial Number U1111-1141-6595.

摘要

背景

自杀倾向的治疗可以通过在线方式进行,但需要其有效性的证据。

目的

我们研究的目的是检验与注意力匹配的对照项目相比,一种针对自杀念头的在线自助干预措施的有效性。

方法

进行了一项双臂随机对照试验,在干预后、6个月和12个月进行评估。通过媒体和社区宣传,招募了418名有自杀倾向的成年人进入一个在线平台,并为他们提供干预项目(与致命念头共处)或对照项目(生活得好)。主要结局是自杀念头的严重程度,使用哥伦比亚自杀严重程度评定量表进行评估。

结果

意向性分析显示,在干预后、6个月和12个月时,自杀念头的严重程度显著降低。然而,未发现总体组间差异。

结论

与致命念头共处并不比对照组更有效。现在需要进一步研究该项目可能有益的条件。该试验的局限性包括鉴于最终观察到的效应量,样本量不足、脱落率高,以及无法确定自杀死亡情况或核实自我报告的自杀未遂情况。

试验注册

澳大利亚新西兰临床试验注册中心ACTRN12613000410752;https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364016(由WebCite存档于http://www.webcitation.org/6vK5FvQXy);通用试验编号U1111-1141-6595。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c325/5830610/c41366f01d12/jmir_v20i2e15_fig1.jpg

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