UniversitatsSpital Zurich Klinik fur Neuroradiologie, Zurich, Switzerland.
Moyamoya Center, Universitats-Kinderspital Zurich, Zurich, Switzerland.
J Neurointerv Surg. 2018 Jun;10(6):e14. doi: 10.1136/neurintsurg-2017-013464.rep. Epub 2018 Feb 14.
Here we report, for the first time, a combination of five-vessel aortic arch, anomalous origin of the right vertebral artery (VA) from the common carotid artery (CCA), an aberrant right subclavian artery (SCA), and bilateral symmetrical segmental agenesis of VAs.In this case report, we present a patient with moyamoya syndrome (MMS) and Down syndrome (DS) who has bilateral symmetrical segmental agenesis of VAs, left VA originating from aortic arch and anomalous origin of right VA arising from CCA in combination with an aberrant right SCA. Therefore, five vessels are originating from aortic arch. Here, we report, for the first time, a combination of five-vessel aortic arch with an aberrant right SCA and symmetrical segmental agenesis of both VAs. The possible embryological mechanisms of the anomalies as well as an relation with MMS and DS are discussed.
在这里，我们首次报告了一种五血管主动脉弓的组合，包括右椎动脉（VA）异常起源于颈总动脉（CCA）、右锁骨下动脉（SCA）异常以及双侧对称节段性 VA 发育不全。在本病例报告中，我们介绍了一位患有烟雾病（MMS）和唐氏综合征（DS）的患者，该患者双侧对称节段性 VA 发育不全，左侧 VA 起源于主动脉弓，右侧 VA 异常起源于 CCA，并伴有右 SCA 异常。因此，有五支血管发自主动脉弓。在这里，我们首次报告了一种五血管主动脉弓的组合，伴有右 SCA 异常和双侧对称节段性 VA 发育不全。讨论了这些异常的可能胚胎发生机制以及与 MMS 和 DS 的关系。
