On the stimulating capacity of human leukemic REH cells in a mixed lymphocyte culture.

In contrast to earlier studies, the presence of a stimulating capacity of cultured leukemic REH cells in a mixed lymphocyte culture is demonstrated. Supernatants of REH cells in a 1:10 final dilution were found to inhibit lymphocyte proliferation by about 30%. Mycoplasma contamination may introduce serious artefacts in all experimental systems which detect lymphocyte proliferation by means of incorporation of 3H-thymidine.