淋巴细胞增生性疾病患者淋巴细胞的混合淋巴细胞培养刺激和反应能力。
Mixed lymphocyte culture stimulatory and responding capacity of lymphocytes from patients with lymphoproliferative diseases.
作者信息
Rühl H, Vogt W, Bochert G, Schmidt S, Moelle R, Schaoua H
出版信息
Clin Exp Immunol. 1975 Jan;19(1):55-65.
Abstract
Lymphocyte reactivity in vitro was studied in patients with Hodgkin's disease, chronic lymphocytic leukaemia and lymphosarcoma. The responding capacity to phytohaemagglutinin (PHA) was markedly depressed and delayed in all three groups of patients compared with the PHA response observed in lymphocyte cultures from normal individuals. In one-way mixed lymphocyte culture experiments a significant decrease in responding capacity of the patients' lymphocytes to lymphocytes from normal donors could be demonstrated. In contrast, the stimulatory capacity of the patients' lymphocytes was found to be intact, or only slightly reduced.
摘要
对霍奇金病、慢性淋巴细胞白血病和淋巴肉瘤患者的淋巴细胞体外反应性进行了研究。与正常个体淋巴细胞培养物中观察到的植物血凝素（PHA）反应相比，这三组患者对PHA的反应能力均明显降低且延迟。在单向混合淋巴细胞培养实验中，可以证明患者淋巴细胞对正常供体淋巴细胞的反应能力显著下降。相比之下，发现患者淋巴细胞的刺激能力是完整的，或仅略有降低。
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Mixed lymphocyte culture stimulatory and responding capacity of lymphocytes from patients with lymphoproliferative diseases.淋巴细胞增生性疾病患者淋巴细胞的混合淋巴细胞培养刺激和反应能力。
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Immunological capacity of lymphocytes from untreated patients with Hodgkin's disease evaluated in mixed lymphocyte culture.在混合淋巴细胞培养中评估未经治疗的霍奇金病患者淋巴细胞的免疫能力。
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