Savchenkov M F, Efimova N V, Manueva R S, Nikolaeva L A, Shin N S
Gig Sanit. 2016;95(12):1201-5.
The article presents results of study of the impact of iodine deficiency and technogenic fluoride on the state of the thyroid gland in children. On the example of two districts of the city of Bratsk there were executed dynamic investigations (2002 and 2012), including the estimation of the pollution of ambient air and soil by fluorine compounds, levels of iodine intake by the body, the clinical examination of children aged from 5 to 7 years d and interviewing of their parents. In the course of the medical examination there were executed: physical examination by the pediatrician, endocrinologist, ultrasound examination of the thyroid gland, the determination both of serum hormone content by radioimmunoassay and urinary excretion offluorine and iodine. Concentrations of hydrogen fluoride and a solidfluorides in ambient air led to the accumulation offluoride ion in the soil. The iodine entering with drinking water and food, was established to provide only 37.5-50% of the daily requirement of iodine. Increased fluoride ion content in urine and milk teeth in children is associated with the concentrations of the fluorine-containing pollutants in the ambient air and soil. The fluoride pollution against the background of the natural iodine deficiency was established to increase the frequency of functional and morphological disorders of the thyroid gland in children.
本文介绍了碘缺乏和技术源氟对儿童甲状腺状态影响的研究结果。以布拉茨克市两个区为例进行了动态调查（2002年和2012年），包括评估环境空气和土壤中氟化合物的污染情况、人体碘摄入量、对5至7岁儿童的临床检查以及对其父母的访谈。在医学检查过程中进行了：儿科医生和内分泌科医生的体格检查、甲状腺超声检查、通过放射免疫分析法测定血清激素含量以及测定尿氟和尿碘排泄量。环境空气中氟化氢和固态氟化物的浓度导致土壤中氟离子的积累。经确定，通过饮用水和食物摄入的碘仅满足每日碘需求量的37.5 - 50%。儿童尿中氟离子含量增加以及乳牙中氟含量增加与环境空气和土壤中含氟污染物的浓度有关。经确定，在天然碘缺乏的背景下，氟污染会增加儿童甲状腺功能和形态紊乱的发生率。
