家庭脉压预测 2 型糖尿病患者动脉僵硬度的阈值：神户 HBP 研究。
Threshold value of home pulse pressure predicting arterial stiffness in patients with type 2 diabetes: KAMOGAWA-HBP study.
机构信息
Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Department of Organ Transplantation and General Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
出版信息
J Clin Hypertens (Greenwich). 2018 Mar;20(3):472-477. doi: 10.1111/jch.13209. Epub 2018 Feb 15.
This cross-sectional multicenter study was designed to evaluate the threshold value of home pulse pressure (PP) and home systolic blood pressure (SBP) predicting the arterial stiffness in 876 patients with type 2 diabetes. We measured the area under the receiver-operating characteristic curve (AUC) and estimated the ability of home PP to identify arterial stiffness using Youden-Index defined cut-off point. The arterial stiffness was measured using the brachial-ankle pulse wave velocity (baPWV). AUC for arterial stiffness in morning PP was significantly greater than that in morning SBP (P < .001). AUC for arterial stiffness in evening PP was also significantly greater than that in evening SBP (P < .001). The optimal cut-off points for morning PP and evening PP, which predicted arterial stiffness, were 54.6 and 56.9 mm Hg, respectively. Our findings indicate that we should pay more attention to increased home PP in patients with type 2 diabetes.
本横断面多中心研究旨在评估 876 例 2 型糖尿病患者家庭脉压 (PP) 和家庭收缩压 (SBP) 的阈值，以预测动脉僵硬度。我们测量了受试者工作特征曲线下面积 (AUC)，并使用 Youden 指数定义的切点估计了家庭 PP 识别动脉僵硬度的能力。使用肱踝脉搏波速度 (baPWV) 测量动脉僵硬度。清晨 PP 预测动脉僵硬度的 AUC 明显大于清晨 SBP (P<.001)。傍晚 PP 预测动脉僵硬度的 AUC 也明显大于傍晚 SBP (P<.001)。预测动脉僵硬度的清晨 PP 和傍晚 PP 的最佳截断点分别为 54.6 和 56.9mmHg。我们的研究结果表明，我们应该更加关注 2 型糖尿病患者家庭 PP 的增加。
Zotero 插件