Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
Cell Host Microbe. 2018 Feb 14;23(2):147-148. doi: 10.1016/j.chom.2018.01.015.
Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggered IBD (Burger et al., 2018; Matsuzawa-Ishimoto et al., 2017; Pott et al., 2018).
自噬与炎症性肠病（IBD）在遗传上有关联；然而，其在疾病发病机制中的作用仍不清楚。最近的三项研究揭示了自噬在病毒、细菌和原生动物引发的 IBD 中的一种新的细胞保护作用（Burger 等人，2018 年；Matsuzawa-Ishimoto 等人，2017 年；Pott 等人，2018 年）。
