Buonanno C
G Ital Cardiol. 1986 Jun;16(6):457-62.
Transluminal coronary angioplasty is a complex technique, and a lesser percentage of success, or "learning curve", is reported in the initial experience of several investigators. Is reported here an initial series of 20 consecutive cases treated by coronary angioplasty for single vessel coronary disease with favourable results. After a meticulous medical treatment, coronary angioplasty was performed in the 20 cases with a "steerable" catheter and guide system and step-wise pressure inflations. In only 1 case (5%), with highly unstable clinical conditions and "unfavourable anatomy", the technique was followed by emergency aorto-coronary bypass and myocardial infarction. In 19 cases (95%) clinical and angiographic success was obtained, with a significant reduction of the mean measured coronary artery stenosis from 84.8 +/- 10.5% to a post-dilatation value of 15.6 +/- 10.5% (p less than 0.001). Coronary artery occlusion due to spasm or thrombosis or coronary dissection were never observed. This favourable series demonstrates that nowadays with the improved technology and with a scrupulous pharmacological protocol transluminal coronary angioplasty can be performed with a low incidence of complications and excellent results, further assessing its high potential in the treatment of ischemic coronary artery disease.
经腔冠状动脉血管成形术是一项复杂的技术,在几位研究者的初期经验中,成功率较低,即存在“学习曲线”。本文报道了最初连续20例经冠状动脉血管成形术治疗单支冠状动脉疾病的病例系列,结果良好。经过精心的内科治疗后,使用“可操纵”导管和引导系统并逐步进行压力充盈,对这20例患者实施了冠状动脉血管成形术。仅1例(5%)患者临床情况高度不稳定且“解剖结构不利”,术后接受了急诊主动脉冠状动脉搭桥术并发生心肌梗死。19例(95%)患者获得了临床和血管造影成功,平均测量的冠状动脉狭窄程度从84.8±10.5%显著降低至扩张后值15.6±10.5%(p<0.001)。未观察到因痉挛、血栓形成或冠状动脉夹层导致的冠状动脉闭塞。这一良好的病例系列表明,如今随着技术的改进以及严格的药物治疗方案,经腔冠状动脉血管成形术可以在并发症发生率较低且效果良好的情况下实施,进一步评估了其在治疗缺血性冠状动脉疾病方面的巨大潜力。